DeVita, Hellman, and Rosenberg’s Cancer - Principles & Practice of Oncology eleventh 11th edition

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Cover Title Page Editors Copyright Contributing Authors PREFACE ACKNOWLEDGMENT CONTENTS Part I: Molecular Biology of Cancer 1. The Cancer Genome 2. Molecular Methods in Cancer 3. Hallmarks of Cancer: An Organizing Principle for Cancer Medicine 4. Microbiome and Cancer 5. Cancer Susceptibility Syndromes Part II: Etiology and Epidemiology of Cancer Section 1: Etiology of Cancer 6. Tobacco 7. Oncogenic Viruses 8. Inflammation 9. Chemical Factors 10. Physical Factors 11. Dietary Factors 12. Obesity and Physical Activity Section 2: Epidemiology of Cancer 13. Epidemiologic Methods 14. Global Cancer Incidence and Mortality Part III: Cancer Therapeutics 15. Precision Medicine in Oncology 16. Essentials of Radiation Therapy 17. Cancer Immunotherapy 18. Pharmacokinetics and Pharmacodynamics of Anticancer Drugs 19. Pharmacogenomics 20. Alkylating Agents 21. Platinum Analogs 22. Antimetabolites 23. Topoisomerase-Interacting Agents 24. Antimicrotubule Agents 25. Kinase Inhibitors as Anticancer Drugs 26. Histone Deacetylase Inhibitors and Demethylating Agents 27. Proteasome Inhibitors 28. Poly(ADP-Ribose) Polymerase Inhibitors for Tumors with Defects in DNA Repair 29. Miscellaneous Chemotherapeutic Agents 30. Hormonal Agents 31. Monoclonal Antibodies 32. Immunotherapy Agents Part IV: Cancer Prevention and Screening 33. Tobacco Use and the Cancer Patient 34. Role of Surgery in Cancer Prevention 35. Cancer Risk–Reducing Agents 36. Prophylactic Cancer Vaccines 37. Cancer Screening 38. Genetic Counseling Part V: Practice of Oncology 39. Design and Analysis of Clinical Trials 40. Assessment of Clinical Response 41. Vascular Access 42. Endoscopic and Robotic Surgery 43. Tumor Biomarkers Section 1: Cancer of the Head and Neck 44. The Molecular Biology of Head and Neck Cancers 45. Cancer of the Head and Neck 46. Rehabilitation After Treatment of Head and Neck Cancer Section 2: Cancer of the Thoracic Cavity 47. The Molecular Biology of Lung Cancer 48. Non–small-cell Lung Cancer 49. Small Cell and Neuroendocrine Tumors of the Lung 50. Neoplasms of the Mediastinum Section 3: Cancers of the Gastrointestinal Tract 51. Molecular Biology of the Esophagus and Stomach 52. Cancer of the Esophagus 53. Cancer of the Stomach 54. The Molecular Biology of Pancreas Cancer 55. Cancer of the Pancreas 56. Molecular Biology of Liver Cancer 57. Cancer of the Liver 58. Cancer of the Biliary Tree 59. Small Bowel Cancer 60. Gastrointestinal Stromal Tumor 61. Molecular Biology of Colorectal Cancer 62. Cancer of the Colon 63. Cancer of the Rectum 64. Cancer of the Anal Region 65. Molecular Biology of Kidney Cancer Section 4: Cancers of the Genitourinary System 66. Cancer of the Kidney 67. Molecular Biology of Bladder Cancer 68. Cancer of the Bladder, Ureter, and Renal Pelvis 69. The Molecular Biology of Prostate Cancer 70. Cancer of the Prostate 71. Cancer of the Urethra and Penis 72. Cancer of the Testis Section 5: Gynecologic Cancers 73. Molecular Biology of Gynecologic Cancers 74. Cancer of the Cervix, Vagina, and Vulva 75. Cancer of the Uterine Body 76. Gestational Trophoblastic Neoplasia 77. Ovarian Cancer Section 6: Cancer of the Breast 78. Molecular Biology of Breast Cancer 79. Malignant Tumors of the Breast Section 7: Cancer of the Endocrine System 80. Molecular Biology of Endocrine Tumors 81. Thyroid Tumors 82. Parathyroid Tumors 83. Adrenal Tumors 84. Pancreatic Neuroendocrine Tumors 85. Carcinoid Tumors and the Carcinoid Syndrome 86. Multiple Endocrine Neoplasia Section 8: Sarcomas of Soft Tissue and Bone 87. Molecular Biology of Sarcomas 88. Soft Tissue Sarcoma 89. Sarcomas of Bone Section 9: Cancers of the Skin 90. Cancer of the Skin 91. Molecular Biology of Cutaneous Melanoma 92. Cutaneous Melanoma Section 10: Neoplasms of the Central Nervous System 93. Molecular Biology of Central Nervous System Tumors 94. Neoplasms of the Central Nervous System Section 11: Cancers in Adolescents and Young Adults 95. Adolescents and Young Adults with Cancer 96. Molecular Biology of Lymphoma Section 12: Lymphomas in Adults 97. Hodgkin Lymphoma 98. Non-Hodgkin Lymphoma 99. Cutaneous Lymphomas 100. Primary Central Nervous System Lymphoma Section 13: Leukemias and Plasma Cell Tumors 101. Molecular Biology of Acute Leukemias 102. Management of Acute Leukemias 103. Molecular Biology of Chronic Leukemias 104. Chronic Myeloid Leukemia 105. Chronic Lymphocytic Leukemias 106. Myelodysplastic Syndromes 107. Plasma Cell Neoplasms Section 14: Other Cancers 108. Cancer of Unknown Primary 109. Benign and Malignant Mesothelioma 110. Peritoneal Metastases and Peritoneal Mesothelioma 111. Intraocular Melanoma Section 15: Oncologic Emergencies 112. Superior Vena Cava Syndrome 113. Increased Intracranial Pressure 114. Spinal Cord Compression 115. Metabolic Emergencies Section 16: Treatment of Metastatic Cancer 116. Metastatic Cancer to the Brain 117. Metastatic Cancer to the Lung 118. Metastatic Cancer to the Liver 119. Metastatic Cancer to the Bone 120. Malignant Pleural and Pericardial Effusions 121. Malignant Ascites 122. Paraneoplastic Syndromes Section 17: Stem Cell Transplantation 123. Autologous Hematopoietic Cell Transplantation 124. Allogeneic Stem Cell Transplantation Section 18: Management of Adverse Effects of Treatment 125. Infections in the Cancer Patient 126. Neutropenia and Thrombocytopenia 127. Nausea and Vomiting 128. Diarrhea and Constipation 129. Oral Complications 130. Pulmonary Toxicity 131. Cardiac Toxicity 132. Hair Loss and Other Hair Changes 133. Gonadal Dysfunction 134. Fatigue 135. Second Cancers 136. Neurocognitive Effects 137. Cancer Survivorship Part VI: Palliative and Alternative Care Section 1: Supportive Care and Quality of Life 138. Management of Cancer Pain 139. Nutrition Support 140. Sexual Problems 141. Psychological Issues 142. Communicating News to the Cancer Patient 143. Specialized Care of the Terminally Ill 144. Rehabilitation of the Cancer Patient Section 2: Complementary, Alternative, and Integrative Therapies 145. Complementary, Alternative, and Integrative Therapies in Cancer Care INDEX A B C D E F G H I J K L M N O P Q R S T U V W X Y Z Copyright Title Page Dedication Contents Chapter 1: ‘I’m thinking’ – Oh, but are you? Chapter 2: Renegade perception Chapter 3: The Pushbacker sting Chapter 4: ‘Covid’: The calculated catastrophe Chapter 5: There is no ‘virus’ Chapter 6: Sequence of deceit Chapter 7: War on your mind Chapter 8: ‘Reframing’ insanity Chapter 9: We must have it? So what is it? Chapter 10: Human 2.0 Chapter 11: Who controls the Cult? Chapter 12: Escaping Wetiko Postscript Appendix: Cowan-Kaufman-Morell Statement on Virus Isolation Bibliography Index Copyright Title Page Dedication Contents Chapter 1: ‘I’m thinking’ – Oh, but are you? Chapter 2: Renegade perception Chapter 3: The Pushbacker sting Chapter 4: ‘Covid’: The calculated catastrophe Chapter 5: There is no ‘virus’ Chapter 6: Sequence of deceit Chapter 7: War on your mind Chapter 8: ‘Reframing’ insanity Chapter 9: We must have it? So what is it? Chapter 10: Human 2.0 Chapter 11: Who controls the Cult? Chapter 12: Escaping Wetiko Postscript Appendix: Cowan-Kaufman-Morell Statement on Virus Isolation Bibliography Index