Standards for Ocular Toxicology and Inflammation

Description

This book is an international effort to standardize the language, terms, and methods used in ocular toxicology.With over 300 color illustrations this consensus volume provides standards and harmonization for procedures, terminology, and scoring schemes for ocular toxicology. it is essential for industry, pharmaceutical companies, and governmental agencies to help improve the drug development process and to reduce and refine the use of animals in research. Standards for Ocular Toxicology and Inflammation is endorsed by the American College of Veterinary Ophthalmologists. Front Matter ....Pages i-ix Standards for Conducting Ophthalmic Examinations in Laboratory Animals (David A. Wilkie, Brian C. Gilger, Joshua T. Bartoe)....Pages 1-25 Standard Operating Procedures for Common Laboratory Animal Ocular Procedures (Brian C. Gilger, Joshua T. Bartoe, J. Seth Eaton, Ryan Boyd)....Pages 27-44 Harmonization of Lesion Nomenclature in Laboratory Animals (Joshua T. Bartoe, Cynthia S. Cook, Martin Bussieres, Robert J. Munger, Michael H. Brown)....Pages 45-140 Spontaneous Incidence of Ocular Abnormalities in Laboratory Animals (Brian C. Gilger, Michael H. Brown, Robert J. Munger, Joshua T. Bartoe, Martin Bussieres, Cynthia S. Cook)....Pages 141-168 Standardized Scoring of Ocular Findings in the Context of Drug and Device Development Programs (J. Seth Eaton, Paul E. Miller, Ellison Bentley, Sara M. Thomasy, Christopher J. Murphy)....Pages 169-205 Back Matter ....Pages 207-212