Bioinformatics for Systems Biology

Description

Хорошая, объёмистая книга о биоинформатике на английском языке. В книге неплохо описаны основные концепции молекулярной биологии, популяционной генетики, статистики и конечно же приведено масса методов и концепций бионформатики. Contents 1 Structure and Function of the Nucleus and Cell Organelles 2 Transcription and the Control of Gene Expression 3 RNA Processing and Translation 4 DNA Replication, Recombination, and Repair 5 Cell Signaling 6 Epigenetics of Spermiogenesis – Combining In Silico and Proteomic Approaches in the Mouse Model 7 Genomic Tools for Analyzing Transcriptional Regulatory Networks 8 Probability and Hypothesis Testing 9 Stochastic Models for Biological Patterns 10 Population Genetics 11 Statistical Tools for Gene Expression Analysis and Systems Biology and Related Web Resources 12 What Goes in is What Comes Out: How to Design and Implement a Successful Microarray Experiment 13 Tools and Approaches for an End-to-End Expression Array Analysis 14 Analysis of Alternative Splicing with Microarrays 15 An Introduction to Multiple Sequence Alignment — and the T-Coffee Shop. Beyond Just Aligning Sequences: How Good can you Make your Alignment, and so What? 16 A Spectrum of Phylogenetic-Based Approaches for Predicting Protein Functional Sites 17 The Role of Transcription Factor Binding Sites in Promoters and Their In Silico Detection 18 In Silico Discovery of DNA Regulatory Sites and Modules 19 Mining the Research Literature in Systems Biology 20 GoPubMed: Exploring PubMed with Ontological Background Knowledge 21 BiblioSphere — Hypothesis Generation in Regulatory Network Analysis 22 Biological Knowledge Extraction – A Case Study of iHOP and Other Language Processing Systems 23 Using KEGG in the Transition from Genomics to Chemical Genomics 24 Ensembl – Open-Source Software for Large-Scale Genome Analysis 25 Management of Spatially Organized Biological Data using EMAGE 26 Equality of the Sexes? Parent-of-Origin Effects on Transcription and de novo Mutations 27 Methods for Structural Inference and Functional Module Identification in Intracellular Networks 28 Methods for Dynamical Inference in Intracellular Networks 29 ASIAN: Network Inference Web Server 30 Bioinformatics for Metabolomics 31 Virtual Reality Meets Functional Genomics 32 Systems Biology of Personalized Medicine