Chemoprevention of Cancer and DNA Damage by Dietary Factors
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Description
This reference work provides a comprehensive overview of the field of dietary chemoprevention of cancer. It reviews the wide variety of dietary factors and mechanisms of anticarcinogenesis and antimutagenesis that have been identified in vitro and in animal and human studies. This volume covers the most recent molecular mechanism by which dietary antimutagens and anticarcinogens function, and also notes the needs for further research in this potentially important area of public health. It is a must-have reference for nutritional scientists, medicinal chemists, food scientists, biotechnologists, pharmacists, and molecular biologists working in academia or the pharmaceutical and food industries, as well as governmental and regulatory agencies concerned with nutrition and cancer. With a foreword by Bruce N. Ames. Sections of the book: ? General Principles ? Experimental Models and Methods Used in Chemoprevention ? Selected Chemoprotective Dietary Factors and ComponentsContent: Chapter 1 Molecular Mechanisms of Cancer Induction and Chemoprevention (pages 1–19): Helmut Bartsch and Dr. Clarissa GerhauserChapter 2 Types and Consequences of DNA Damage (pages 21–33): Daniel T. Shaughnessy and Dr. David M. DeMariniChapter 3 Induction of DNA Damage and Cancer by Dietary Factors (pages 35–55): Wolfram Parzefall, Nina Kager and Prof. Dr. Siegfried KnasmullerChapter 4 Mechanisms of Chemoprevention, Antimutagenesis, and Anticarcinogenesis: An Overview (pages 57–72): Silvio De Flora, Carlo Bennicelli, Alessandra Battistella and Maria BagnascoChapter 5 Antioxidants and Cancer: Fact and Fiction (pages 73–92): Andrew R. Collins and Alain FavierChapter 6 Xenobiotic Metabolism: A Target for Nutritional Chemoprevention of Cancer? (pages 93–108): Hansruedi GlattChapter 7 Dietary Factors Regulate Metabolism of Carcinogens through Transcriptional Signaling Pathways (pages 109–120): Soona Shin and Thomas W. KenslerChapter 8 Endocrine?Related Cancers and Phytochemicals (pages 121–143): Johannes C. Huber and Johannes OttChapter 9 Inflammation?Induced Carcinogenesis and Chemoprevention (pages 145–152): Hiroshi Ohshima, Susumu Tomono, Ying?Ling Lai and Noriyuki MiyoshiChapter 10 DNA Methylation (pages 153–162): Prof. Ian T. Johnson, Nigel J. Belshaw and Giles O. ElliottChapter 11 Prevention of Angiogenesis and Metastasis (pages 163–182): Tariq A. Bhat, Anil Mittal and Rana P. SinghChapter 12 Impact of Dietary Factors on the Immune System (pages 183–198): Alexa L. MeyerChapter 13 Epidemiological Studies (pages 199–208): Anthony B. MillerChapter 14 Methods Used for the Detection of Antimutagens: An Overview (pages 209–227): Armen Nersesyan, Miroslav Misik and Prof. Dr. Siegfried KnasmullerChapter 15 Methods to Determine Total Antioxidative Capacity and Oxidative DNA Damage (pages 229–244): Karl?Heinz Wagner, Miroslav Misik, Armen Nersesyan and Prof. Dr. Siegfried KnasmullerChapter 16 Measurement of Enzymes of Xenobiotic Metabolism in Chemoprevention Research (pages 245–261): Wolfgang W. Huber and Michael GruschChapter 17 Methods for the Analysis of DNA Methylation (pages 263–276): Keith N. Rand and Peter L. MolloyChapter 18 Methods Used to Study Alterations of Cell Signaling and Proliferation (pages 277–289): Dr. Clarissa GerhauserChapter 19 Methods for the Assessment of Antiangiogenic Activity (pages 291–301): Dr. Clarissa GerhauserChapter 20 Nutrigenomics (pages 303–333): Jan Frank and Gerald RimbachChapter 21 Preneoplastic Models and Carcinogenicity Studies with Rodents (pages 335–356): Veronika A. Ehrlich and Prof. Dr. Siegfried KnasmullerChapter 22 The Role of Nutrition in the Etiology of Human Cancer: Methodological Considerations Concerning Epidemiological Studies (pages 357–367): Heiner BoeingChapter 23 Carotenoids and Vitamin A (pages 369–383): M. Cristina Polidori and Wilhelm StahlChapter 24 Selected Vitamins (pages 385–415): Pavel Kramata, Nanjoo Suh, Heide S. Cross, Thomas Nittke and Hong Jin LeeChapter 25 Folate and Vitamins B2, B6, and B12 (pages 417–433): Philip Thomas and Michael FenechChapter 26 Micronutrients and Susceptibility to Cancer: Focus on Selenium and Zinc (pages 435–453): Dianne Ford and John HeskethChapter 27 DNA Damage and Cancer Chemoprevention by Polyphenols (pages 455–482): Ajaikumar B. Kunnumakkara, Preetha Anand, Kuzhuvelil B. Harikumar and Bharat B. AggarwalChapter 28 Antioxidant, Anti?Inflammatory, and Anticarcinogenic Effects of Ginger and Its Ingredients (pages 483–498): Hye?Kyung Na, Joydeb Kumar Kundu and Young?Joon SurhChapter 29 Tannins: Bioavailability and Mechanisms of Action (pages 499–508): Fulgencio Saura?Calixto and Jara Perez?JimenezChapter 30 Selected Flavonoids (pages 509–545): Loic Le Marchand, Adrian A. Franke, Li?Shu Wang, Gary D. Stoner and Dr. Clarissa GerhauserChapter 31 Phytoestrogens (pages 547–577): Alicja Mortensen, Sabine Kulling, Heidi Schwartz, Gerhard Sontag, Eric Laine, Christophe Hano and Frederic LamblinChapter 32 Chemopreventive Properties of Coffee and Its Constituents (pages 579–594): Gernot Faustmann, Christophe Cavin, Armen Nersesyan and Prof. Dr. Siegfried KnasmullerChapter 33 Tea and Its Constituents (pages 595–633): Joshua D. Lambert, Chung S. Yang, Wentzel C. A. Gelderblom, Kareemah Gamieldien and Elizabeth JoubertChapter 34 Protective Effects of Alcoholic Beverages and their Constituent (pages 635–661): Philipp Saiko, Akos Szakmary, Thomas Szekeres, Metka Filipic, Janja Plazar and Sakae Arimoto?KobayashiChapter 35 Sulfides in Allium Vegetables (pages 663–684): Claus Jacob and Awais AnwarChapter 36 Glucosinolates and Cruciferous Vegetables (pages 685–698): L. Adele Boyd, Cris Gill, Tomas Borkowski and Ian RowlandChapter 37 Chlorophyll (pages 699–708): Hikoya Hayatsu, Tomoe Negishi and Sakae Arimoto?KobayashiChapter 38 Dietary Fibers (pages 709–719): Philip J. Harris and Lynnette R. FergusonChapter 39 Dietary Fiber Carbohydrates and their Fermentation Products (pages 721–729): Lynnette R. Ferguson and Philip J. HarrisChapter 40 Lactobacilli and Fermented Foods (pages 731–747): Sabine Fuchs, Reinhard Stidl, Verena Koller, Gerhard Sontag, Armen Nersesyan and Prof. Dr. Siegfried KnasmullerChapter 41 Fatty Acids and Cancer Prevention (pages 749–760): Elizabeth K. LundChapter 42 Protease Inhibitors (pages 761–767): Ann R. Kennedy
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