ENGLISH

Combination Vaccines: Development, Clinical Research and Approval

By Ronald W. Ellis

Book information

Publisher
Humana Press
Year
1999
ISBN
0896037177, 9780896037175, 9780585262291
LCC
RM281 .C65 1999
Open Library ID
OL390027M
Language
english
Format
EPUB
Filesize
779 kB (798203 bytes)
Edition
1
Pages
\0
Time added
2011-08-31 04:54:40

Description

A diverse team of leading experts comprehensively review the complex biology of a wide variety of vaccine combinations, as well as the technical, clinical, and regulatory aspects of their development. Topics covered range from the use of immunological correlates of efficacy, rather than efficacy per se, for the evaluation and licensure of vaccine combinations, to preserving a stable immunogenic mixture in appropriate containers according to accepted regulatory standards. Discussed in detail are the trivalent influenza vaccine, the pneumococcal polysaccharide vaccine, the MMR vaccine, the DTP vaccine and its combinations, and the quadrivalent rotavirus vaccine, all of which serve as models for the development of future combinations. Combination Vaccines: Development, Clinical Research, and Approval illuminates all the scientific, clinical, regulatory, and health care issues involved in the research, development, and human use of combination vaccines.

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