ENGLISH

Drug Targeting Organ-Specific Strategies

By Raimund Mannhold , Hugo Kubinyi , Hendrik Timmerman , Grietje Molema , Dirk K. F. Meijer

Book information

Publisher
Wiley-VCH
Year
2001
ISBN
9783527299898, 3527299890
LCC
RM301.63 .D78 2001
Open Library ID
OL3968851M
Language
english
Format
PDF
Filesize
4 MB (3938471 bytes)
Edition
1st
Pages
406\406
Library
ihtik
Time added
2009-07-20 05:12:22

Description

How are medicines transported intact through the body to their specific target sites without triggering side effects? The answer is "Drug Targeting".This thoroughly application-oriented book gives comprehensive answers to this and many other questions that confront scientists daily in chemical, pharmaceutical and medical research. A concise overview of the most important basic theories, modern forms of therapy and molecular biological tools, it represents a comprehensible introduction to the topic. The book then goes on to deal with strategies for target applications, divided according to target site, for example brain, lungs, liver, blood vessels and tumor cells. The third part is devoted to special, modern techniques, from phage display methods, via the use of tissue slices right up to pharmacokinetic modeling. Throughout, the focus remains on the practical aspect and successful application of the method in question, although a glance at what the future holds is also included. A volume that every pharmaceutically oriented research group should own.

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