ENGLISH

Drug Resistance in the Treatment of Cancer (Cancer: Clinical Science in Practice)

By Giuseppe Giaccone , Herbert M. Pinedo

Book information

Year
1998
ISBN
0521473217, 9780521473217, 0521030749, 9780521030748, 9780511526992
LCC
RC271.C5 D7778 1998
Open Library ID
OL661062M
Language
english
Format
PDF
Filesize
8 MB (8389679 bytes)
Edition
1
Pages
339\338
Topic
Medicine Oncology
Time added
2011-06-04 13:46:07

Description

The development of drug-resistant cancers is considered to be the most significant obstacle to the cure of cancer today. Nearly half of all patients with cancer suffer from tumors that are intrinsically resistant to chemotherapy, and most of the remaining half develop drug resistance during the course of their treatment. This book reviews the mechanisms and clinical implications of drug resistance in cancer with unrivaled authority. The authors, who are among the leading clinicians and investigators in the field, cover topics of current clinical concern, including multiple drug resistance and its reversal, topoisomerase drugs, apoptosis, dose intensity and escalation, gene therapy and hematopoietic support.

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