Lessons on Caffeine, Cannabis & Co: Plant-derived Drugs and their Interaction with Human Receptors

Description

This textbook provides a structured, easy to understand and thorough insight into the mode of function of plant secondary metabolites in plants and humans. It explains the biosynthesis and molecular action of nicotine, cannabis, caffeine and Co, describes the effects of these drugs on signal transduction at receptors and ion channels in animals, their relevance for human health and their potential for recreational use and abuse. It also offers a broad and comprehensive understanding on the role and function of these diverse molecules for the plants that make them. This textbook is written for master students and scientist in biochemistry and biology as well as for pharmaceutical and medical students. It will be a valuable study tool for teachers and students alike. Front Matter ....Pages I-X Front Matter ....Pages 1-1 Plant Secondary Metabolites and Their General Function in Plants (Angelika Böttger, Ute Vothknecht, Cordelia Bolle, Alexander Wolf)....Pages 3-17 Historical and Current Perspective (Angelika Böttger, Ute Vothknecht, Cordelia Bolle, Alexander Wolf)....Pages 19-25 Front Matter ....Pages 27-27 GPCRs (Angelika Böttger, Ute Vothknecht, Cordelia Bolle, Alexander Wolf)....Pages 29-42 Ion Channels (Angelika Böttger, Ute Vothknecht, Cordelia Bolle, Alexander Wolf)....Pages 43-56 GPCRs as Targets for Plant-Derived Drugs (Angelika Böttger, Ute Vothknecht, Cordelia Bolle, Alexander Wolf)....Pages 57-82 Ion Channels as Targets for Plant-Derived Drugs (Angelika Böttger, Ute Vothknecht, Cordelia Bolle, Alexander Wolf)....Pages 83-95 Front Matter ....Pages 97-97 Plant-Derived Drugs Affecting GPRCs (Angelika Böttger, Ute Vothknecht, Cordelia Bolle, Alexander Wolf)....Pages 99-120 Plant-Derived Drugs Affecting Ion Channels (Angelika Böttger, Ute Vothknecht, Cordelia Bolle, Alexander Wolf)....Pages 121-140 Front Matter ....Pages 141-142 Secondary Metabolites in Plants: General Introduction (Angelika Böttger, Ute Vothknecht, Cordelia Bolle, Alexander Wolf)....Pages 143-152 Terpenes and Terpenoids (Angelika Böttger, Ute Vothknecht, Cordelia Bolle, Alexander Wolf)....Pages 153-170 Phenylpropanoids (Angelika Böttger, Ute Vothknecht, Cordelia Bolle, Alexander Wolf)....Pages 171-178 Alkaloids (Angelika Böttger, Ute Vothknecht, Cordelia Bolle, Alexander Wolf)....Pages 179-203 Minor Groups of Secondary Metabolites (Angelika Böttger, Ute Vothknecht, Cordelia Bolle, Alexander Wolf)....Pages 205-214 Back Matter ....Pages 215-217