ENGLISH

Proteostasis and Disease: From Basic Mechanisms to Clinics (Advances in Experimental Medicine and Biology, 1233)

Book information

Publisher
Springer
Year
2020
ISBN
3030382656, 9783030382650
Language
english
Format
PDF
Filesize
8 MB (8825055 bytes)
Pages
360\350
Time added
2024-04-22 22:49:26

Description

This book, written by members of the European network PROTEOSTASIS, provides an up-to-date review of the research regarding protein homeostasis in health and disease. With new discoveries contributing to the increasing complexity of this topic, the book offers a detailed overview of the pathways regulating protein homeostasis, including autophagy and the ubiquitin protein family. Following a basic introduction, it explains how defects in protein homeostasis contribute to numerous pathologies, including cancer, neurodegeneration, inflammation and a number of rare diseases. In addition, it discusses, the role of protein homeostasis in cellular development and physiology. Highlighting the latest research in the field of protein homeostasis and its implications for various clinically relevant diseases, the book appeals to researchers and clinicians, while also offering a reference guide for scholars who are new to the field.

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