Harper's Illustrated Biochemistry

Description

Gain a thorough understanding of the principles of biochemistry as they relate to clinical medicine The Thirty-Second Edition of Harper's Illustrated Biochemistry combines top-quality full-color illustrations with authoritative integrated coverage of biochemical disease and clinical information. Featuring numerous medically relevant examples, this respected text presents a clear, succinct review of the fundamentals that every student must understand in order to succeed in medical school. All 58 chapters help you understand the medical relevance of biochemistry. Full-color presentation with 600+ illustrations Chapters have been updated to reflect the latest information Case studies emphasize the clinical relevance of biochemistry Review questions follow each of the 11 sections Boxed objectives define the goals of each chapter Tables encapsulate important information Each chapter contains a section on biomedical importance and a summary of the topics covered Applauded by medical students for its current and engaging style, Harper’s Illustrated Biochemistry is an essential for USMLE review and the single best reference for learning the clinical relevance of any biochemistry topic. Cover Harper's Illustrated Biochemistry Copyright Co-Authors Contents Preface Section I Structures & Functions of Proteins & Enzymes 1 Biochemistry & Medicine 2 Water & pH 3 Amino Acids & Peptides 4 Proteins: Determination of Primary Structure 5 Proteins: Higher Orders of Structure Section II Enzymes: Kinetics, Mechanism, Regulation, & Role of Transition Metals 6 Proteins: Myoglobin & Hemoglobin 7 Enzymes: Mechanism of Action 8 Enzymes: Kinetics 9 Enzymes: Regulation of Activities 10 The Biochemical Roles of Transition Metals Section III Bioenergetics 11 Bioenergetics: The Role of ATP 12 Biologic Oxidation 13 The Respiratory Chain & Oxidative Phosphorylation Section IV Metabolism of Carbohydrates 14 Overview of Metabolism & the Provision of Metabolic Fuels 15 Saccharides (ie, Carbohydrates) of Physiological Significance 16 The Citric Acid Cycle: A Pathway Central to Carbohydrate, Lipid, & Amino Acid Metabolism 17 Glycolysis & the Oxidation of Pyruvate 18 Metabolism of Glycogen 19 Gluconeogenesis & the Control of Blood Glucose 20 The Pentose Phosphate Pathway & Other Pathways of Hexose Metabolism Section V Metabolism of Lipids 21 Lipids of Physiologic Significance 22 Oxidation of Fatty Acids: Ketogenesis 23 Biosynthesis of Fatty Acids & Eicosanoids 24 Metabolism of Acylglycerols & Sphingolipids 25 Lipid Transport & Storage 26 Cholesterol Synthesis, Transport, & Excretion Section VI Metabolism of Proteins & Amino Acids 27 Biosynthesis of the Nutritionally Nonessential Amino Acids 28 Catabolism of Proteins & of Amino Acid Nitrogen 29 Catabolism of the Carbon skeletons of Amino Acids 30 Conversion of Amino Acids to Specialized Products 31 Porphyrins & Bile Pigments Section VII Structure, Function, & Replication of Informational Macromolecules 32 Nucleotides 33 Metabolism of Purine & Pyrimidine Nucleotides 34 Nucleic Acid Structure & Function 35 DNA Organization, Replication, & Repair 36 RNA Synthesis, Processing, & Modification 37 Protein Synthesis & the Genetic Code 38 Regulation of Gene Expression 39 Molecular Genetics, Recombinant DNA, & Genomic Technology Section VIII Biochemistry of Extracellular & Intracellular Communication 40 Membranes: Structure & Function 41 The Diversity of the Endocrine System 42 Hormone Action & Signal Transduction Section IX Special Topics (A) 43 Nutrition, Digestion, & Absorption 44 Micronutrients: Vitamins & Minerals 45 Free Radicals & Antioxidant Nutrients 46 Glycoproteins 47 Metabolism of Xenobiotics 48 Clinical Biochemistry Section X Special Topics (B) 49 Intracellular Traffic & Sorting of Proteins 50 The Extracellular Matrix 51 Muscle & the Cytoskeleton 52 Plasma Proteins & Immunoglobulins 53 Red Blood Cells 54 White Blood Cells Section XI Special Topics (C) 55 Hemostasis & Thrombosis 56 Cancer: An Overview 57 The Biochemistry of Aging 58 Biochemical Case Histories Index