Dioxins and Health

Description

Dioxins and Health......Page 2 Copyright......Page 4 Contents......Page 6 Contributors......Page 8 Preface......Page 12 1 Overview: The Dioxin Debate......Page 16 2 Production, Distribution, and Fate of Polychlorinated Dibenzo-p-Dioxins, Dibenzofurans, and Related Organohalogens in the Environment......Page 69 3 Dioxins and Dioxinlike PCBs in Food......Page 102 4 Toxicology of Dioxins and Dioxinlike Compounds......Page 150 5 Health Risk Characterization of Dioxins and Related Compounds......Page 171 6 Pharmacokinetics of Dioxins and Related Chemicals......Page 203 7 Dose-Response Modeling for 2,3,7,8-Tetrachlorodibenzo-p-Dioxin......Page 259 8 Immunotoxicology of Dioxins and Related Chemicals......Page 311 9 Developmental and Reproductive Toxicity of Dioxins and Related Chemicals......Page 341 10 Effects of Polychlorinated Biphenyls on Neuronal Signaling......Page 444 11 Experimental Toxicology: Carcinogenesis......Page 467 12 Ah Receptor: Involvement in Toxic Responses......Page 501 13 Biochemical Responses to Dioxins: Which Genes? Which Endpoints?......Page 543 14 Evolutionary and Physiological Perspectives on Ah Receptor Function and Dioxin Toxicity ......Page 569 15 Dioxin Toxicity and Aryl Hydrocarbon Receptor Signaling in Fish......Page 613 16 Exposure Assessment: Measurement of Dioxins and Related Chemicals in Human Tissues......Page 639 17 Human Health Effects of Polychlorinated Biphenyls......Page 689 18 Epidemiological Studies on Cancer and Exposure to Dioxins and Related Compounds ......Page 739 19 Reproductive and Developmental Epidemiology of Dioxins......Page 775 20 Health Consequences of the Seveso, Italy, Accident......Page 836 21 The Yusho Rice Oil Poisoning Incident......Page 863 22 The Yucheng Rice Oil Poisoning Incident......Page 900 Index......Page 927