ENGLISH

Medical Applications of iPS Cells: Innovation in Medical Sciences

By Haruhisa Inoue , Yukio Nakamura

Book information

Publisher
Springer Singapore
Year
2019
ISBN
978-981-13-3671-3;978-981-13-3672-0
Language
english
Format
PDF
Filesize
4 MB (4392204 bytes)
Series
Current Human Cell Research and Applications
Edition
1st ed.
Pages
X, 190\191
Time added
2019-09-18 12:22:33
Medicine & Public Health; Oncology; Cell Biology

Description

This volume highlights recent advances using iPS cells in disease modeling and medical applications along with new technologies that enhance the power of iPS cells. While the discovery of iPS cells has provided excellent opportunities for developing models of human diseases, platforms for drug discovery and cell therapies, iPS cell technology still faces many challenges. Presenting the latest advances in this rapidly evolving research area, this book is intended to widen the community of researchers and clinicians interested in the exciting field of iPS cells. Front Matter ....Pages i-x Front Matter ....Pages 1-1 Clinical Potential of Induced Pluripotent Stem Cells (Peter Karagiannis)....Pages 3-12 Front Matter ....Pages 13-13 Disease Modeling of Hematological and Immunological Disorders Using Induced Pluripotent Stem Cells (Megumu K. Saito)....Pages 15-27 iPS Cell Technology for Dissecting Cancer Epigenetics (Hirofumi Shibata, Yasuhiro Yamada)....Pages 29-43 Recapitulating Hematopoietic Development in a Dish (Kim Vanuytsel, Martin H. Steinberg, George J. Murphy)....Pages 45-71 Modeling Cardiomyopathies with iPSCs (Jean-Sébastien Hulot)....Pages 73-95 Front Matter ....Pages 97-97 Endogenous Signal-Responsive Transgene Switch Systems for Visualization and Purification of Specific Cells (Hideyuki Nakanishi, Hirohide Saito)....Pages 99-112 Precision Genome Editing in Human-Induced Pluripotent Stem Cells (Knut Woltjen)....Pages 113-130 Front Matter ....Pages 131-131 Induced Pluripotent Stem Cell-Based Cell Therapy of the Retina (Seiji Takagi, Michiko Mandai, Yasuhiko Hirami, Yasuo Kurimoto, Masayo Takahashi)....Pages 133-147 Organoid Models of Development and Disease Towards Therapy (Yasunori Nio, Takanori Takebe)....Pages 149-168 In Vivo Cell Conversion as a New Cell Therapy (Hedong Li, Lei Zhang, Yuchen Chen, Zheng Wu, Zhuofan Lei, Gong Chen)....Pages 169-190

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