Handbook of New Genetic Diagnostic Technologies in Reproductive Medicine: Improving Patient Success Rates and Infant Health

Description

Different genetic diagnostic and treatment options are used worldwide to improve routine IVF procedures for the benefit of patients. This handbook updates the new genetic diagnostic technologies that have been translated to practice aiming to improve outcomes in the clinic and have a healthy baby at home. Chapters cover the use of genetic technologies in a personalized manner to unravel the possible genetic risks for the couple wishing to conceive, in terms of sperm, the embryo, the endometrium, miscarriage, and finally the fetus. Content: Carrier screening for single gene disorders / Julio Martin, Beatriz Rodriguez, Arantxa Hervas, and Ana Bover -- Meiotic abnormalities in infertile males / Zaida Serrate, Joan Blanco, and Francesca Vidal -- Chromosomal analysis of sperm / Lorena Rodrigo Vivó, Vanessa Peinado Cervera, and Lucía Marín López -- DNA fragmentation in sperm : does it matter? / Nicolás Garrido, María Gil, and Rocío Rivera -- Aneuploidy in human oocytes and preimplantation embryos / Eva R. Hoffmann, Alan H. Handyside, and Antonio Capalbo -- Preimplantation genetic diagnosis for aneuploidy : all you need to know / Carmen Rubio, Maria Vera, Pilar López, Maria Eugenia Poo, and Gary Harton -- Mitochondria and embryo viability / Irene Corachan Garcia, Laura Iñiguez Quiles, and Antonio Diez-Juan -- Preimplantation genetic diagnosis for single gene disorders / Ana Cervero, Jose Antonio Martínez-Conejero, Lucía Sanz-Salvador, Claudia Gil-Sanchís, Maribel Sánchez-Piris, and Alan Thornhill -- Molecular diagnosis of endometrial receptivity / María Ruiz-Alonso, Jose Miravet-Valenciano, Eva Gómez, Carlos Marin, Sergio Cabanillas, Alejandro Rincon, Diana Valbuena, and Carlos Simón -- Chromosome abnormalities in human pregnancy wastage : a review of cytogenetic and molecular analyses / Kathy Hardy and Terry Hassold -- Products of conception : current methodologies and clinical applications / Nasser Al-Asmar, Sandra Garcia-Hererro, Inmaculada Campos-Galindo, Cengiz Cinnioglu, and Marcia Riboldi -- Non-invasive prenatal testing for aneuploidy and beyond / Miguel Milán Sánchez, Emilia Mateu Brull, Pere Mir Pardo, Diana Valbuena Perilla, and David Blesa Jarque -- Obstacles to implementing new technology / David Jimenez -- Dynamics and ethics of reproductive genetics / Guido de Wert and Wybo Dondorp.