The Behavioral Neuroscience of Drug Discrimination
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The goal for this volume is to provide an up-to-date review of the discriminative stimulus properties of major psychoactive drug classes with an emphasis on how this paradigm enhances our understanding of these drugs and how these findings translate from animals to humans. The drug discrimination paradigm applies to both drugs of abuse and drugs for treating mental illnesses, and research from these studies has provided immense translational value for learning about the mechanisms responsible for drug effects in humans. Front Matter ....Pages i-x Drug Discrimination: Historical Origins, Important Concepts, and Principles (Joseph H. Porter, Adam J. Prus, Donald A. Overton)....Pages 3-26 Discriminative Stimulus Effects of Psychostimulants (Michael D. Berquist, William E. Fantegrossi)....Pages 29-49 Discriminative Stimulus Properties of S(−)-Nicotine: “A Drug for All Seasons” (John A. Rosecrans, Richard Young)....Pages 51-94 Cross-Species Translational Findings in the Discriminative Stimulus Effects of Ethanol (Daicia C. Allen, Matthew M. Ford, Kathleen A. Grant)....Pages 95-111 Discriminative Stimulus Effects of Abused Inhalants (Keith L. Shelton)....Pages 113-139 The Discriminative Stimulus Properties of Hallucinogenic and Dissociative Anesthetic Drugs (Tomohisa Mori, Tsutomu Suzuki)....Pages 141-152 Discriminative Stimulus Properties of Phytocannabinoids, Endocannabinoids, and Synthetic Cannabinoids (Jenny L. Wiley, R. Allen Owens, Aron H. Lichtman)....Pages 153-173 Discriminative Stimulus Properties of Opioid Ligands: Progress and Future Directions (Eduardo R. Butelman, Mary Jeanne Kreek)....Pages 175-192 Translational Value of Drug Discrimination with Typical and Atypical Antipsychotic Drugs (Joseph H. Porter, Kevin A. Webster, Adam J. Prus)....Pages 193-212 The Discriminative Stimulus Properties of Drugs Used to Treat Depression and Anxiety (Adam J. Prus, Joseph H. Porter)....Pages 213-241 Pharmacokinetic–Pharmacodynamic (PKPD) Analysis with Drug Discrimination (S. Stevens Negus, Matthew L. Banks)....Pages 245-259 Human Drug Discrimination: Elucidating the Neuropharmacology of Commonly Abused Illicit Drugs (B. Levi Bolin, Joseph L. Alcorn, Anna R. Reynolds, Joshua A. Lile, William W. Stoops, Craig R. Rush)....Pages 261-295 Conditioned Taste Avoidance Drug Discrimination Procedure: Assessments and Applications (Anthony L. Riley, Matthew M. Clasen, Mary A. Friar)....Pages 297-317 A Prospective Evaluation of Drug Discrimination in Pharmacology (Ellen A. Walker)....Pages 319-328
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