Genome and Genomics: From Archaea to Eukaryotes
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Thisbook provides a detailed and up-to-dated information on the genomes belonging to three major life forms on Earth – archaea, prokaryotes and eukaryotes. Each section describes about the genome of a specific group of organisms, such as viruses, archaea, bacteria, eukaryotes and organellar genomes. Individual chapters provide details of their organization, structure, evolution, sequencing strategies and functions. Further, this book discusses the technologies that are applied for genome sequencing; assembly, annotation and gene prediction. Other topics include the genomes of important model organisms, mitochondria genome of Neanderthal fossil, etc. This book also examines the evolution of chloroplast and mitochondria genomes by comparing with bacteria, addresses the diseases that occur in humans due to the mutations in mitochondrial genome, gene therapy and engineering of chloroplast and mitochondrial genomes. Lastly, it features an overview of the role of proteomics, exposomics, connectomics, metabolomics, and microbiomics. This book is a fascinating read for students, lecturers and researchers in the field of genetics, genomics, microbiology and life sciences. Front Matter ....Pages i-xix Structure and Organization of Virus Genomes (K. V. Chaitanya)....Pages 1-30 Archeal Genomics (K. V. Chaitanya)....Pages 31-54 Structure, Function, and Evolution of Bacterial Genomes (K. V. Chaitanya)....Pages 55-87 Orgenellar Genome Analysis (K. V. Chaitanya)....Pages 89-119 Eukaryotic Genome Organization, Regulation, Evolution and Control (K. V. Chaitanya)....Pages 121-180 Genome Sequencing, Assembly, and Annotation (K. V. Chaitanya)....Pages 181-210 Other ‘Omics’ Integrated into Biosciences (K. V. Chaitanya)....Pages 211-241 Applications of Genomics (K. V. Chaitanya)....Pages 243-260 Important Databases Related to Genomes (K. V. Chaitanya)....Pages 261-269 Back Matter ....Pages 271-307
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