ENGLISH

The Paris system for reporting urinary cytology

By Eva M. Wojcik (editor); Dorothy L. Rosenthal (editor); Daniel F. I. Kurtycz (editor)

Book information

Year
2016
ISBN
9783319228631, 3319228633, 9783319228648, 3319228641
Language
english
Format
PDF
Filesize
8 MB (8702156 bytes)
Pages
\177
Time added
2020-06-06 08:12:59

Description

Dedication Foreword From Bethesda to Paris—At Last We Have Standardized Terminology for Urinary Cytology! Prologue Abbreviations Contents Editors Contributors Chapter 1: Pathogenesis of Urothelial Carcinoma Background Two Pathways of Neoplastic Transformation of Urothelium References Chapter 2: Adequacy of Urine Specimens (Adequacy) Introduction The Adequacy Algorithm Volume and Adequacy Adequacy of Instrumented Urinary Tract Cytology Specimens The Less-Than-Optimal Adequacy Category Recommendations References Chapter 3: Negative for High-Grade Urothelial Carcinoma (Negative) Background Definition of Negative for High-Grade Urothelial Carcinoma Criteria of Components of NHGUC Benign Superficial (Umbrella) Urothelial Cells Squamous Epithelial Cells, Both Superficial and Intermediate Glandular Cells Benign Urothelial Tissue Fragments Benign Urothelial Tissue Fragments in Voided Urine Benign Urothelial Tissue Fragments in Instrumented Urine Clusters, Groups, or Sheets of Urothelial Cells Three-Dimensional Urothelial Tissue Fragments with Nephrolithiasis Urothelium with Nephrolithiasis: Sheets or Clusters/Groups Urothelial Changes Characteristic of Infectious Processes Acute Bacterial Infections Characteristic Viral Cytopathic Effects Urothelial Changes Associated with Treatment Effects Radiation Immunotherapy Chemotherapy Seminal Vesicle Cells Bladder Diversion Urine The Rate of Negative Samples in a Usual Laboratory Population Risk of Malignancy References Chapter 4: Atypical Urothelial Cells (AUC) Background Definition Criteria Explanatory Notes Rate and Risk of Malignancy References Chapter 5: Suspicious for High-Grade Urothelial Carcinoma (Suspicious) Background Definition Criteria Explanatory Notes Rate and Risk of Malignancy References Chapter 6: High-Grade Urothelial Carcinoma (HGUC) Background Historical Review of Reporting System of Urine Cytology The Meaning of Positive Urine Cytology The Importance of Tumor Grade as a Prognostic Factor The Cytologic Characteristics of HGUC Definition Histologic Definition of HGUC Histologic Definition of Carcinoma In Situ Cytologic Definition of HGUC Definition of HGUC with Squamous Differentiation Definition of HGUC with Glandular Differentiation Criteria of Malignancy Other Notable Cytomorphologic Features Explanatory Notes Rate of Malignancy Risk of Malignancy References Chapter 7: Low-Grade Urothelial Neoplasia (LGUN) Background Definitions Histologic Definition of Urothelial Papilloma [8] Histologic Definition of Papillary Urothelial Neoplasm of Low Malignant Potential [8] Histologic Definition of Low-Grade Papillary Urothelial Carcinoma [8] Histologic Definition of Urothelial Dysplasia: Flat Low-Grade Intraurothelial Neoplasia [8] Cytologic Definition of Low-Grade Urothelial Neoplasia Cytologic Criteria of LGUN (Regardless of the Specimen Type: Voided or Instrumented) Explanatory Notes Rate of Recurrence and Risk of Progression References Chapter 8: Other Malignancies Primary and Metastatic and Miscellaneous Lesions Primary Non-Urothelial Tumors Epithelial Malignancies Squamous Cell Carcinoma Background Definition Diagnostic Criteria Liquid-Based Preparations (LBP) Adenocarcinoma Background Definition Criteria Neuroendocrine Tumors Small Cell Carcinoma and Large Cell Neuroendocrine Carcinoma Background Definition of SmCC Criteria LBPs [6, 18] (see Figs. 8.15 and 8.16) Non-Epithelial Malignancies Sarcoma Hematologic Malignancy Melanoma Direct Extension and Metastatic Tumors to Urinary bladder Background Direct Extension (Carcinomas of Prostate, Colon, Rectum, Uterine Cervix) AdCa of Prostate Colorectal AdCa SqCC of Uterine Cervix Metastatic Tumors (Renal Cell, Breast, Ovarian, Lung, Stomach and Skin Carcinoma, Melanoma and Hematologic Malignancies) Renal Cell Carcinoma (RCC) Breast Carcinoma Gastric Carcinoma Non-Epithelial Benign Tumors and Tumor-Like Conditions Non-Epithelial Benign Tumors Pheochromocytoma/Paraganglioma Tumor-Like Lesions Nephrogenic Adenoma Amyloidosis Inflammatory Pseudotumor (Pseudosarcomatous Fibromyxoid Tumor) References Chapter 9: Ancillary Studies in Urinary Cytology Background Pre-analytical Procedures, Technique, and Evaluation of UroVysion® FISH Specimen Preparation Analysis of FISH Signals Imaging and Automation of UroVysion® FISH Analysis Advantages of an Automated Imaging System Details of Automated Imaging Systems Target FISH Reporting of Results Performance of UroVysion® FISH Testing UroVysion FISH in Atypical Urinary Cytology Cost-Effectiveness of UroVysion FISH Pitfalls in UroVysion® FISH Analysis ImmunoCyt/uCyt+ and Other Cell-Based Tests ImmunoCyt/uCyt+ Test Other Cell-Based Tests Liquid-Based Tests BTA Test The NMP22 Test Other Liquid-Based Biomarkers Conclusions Sample Reports UroVysion FISH Appendix UroVysion® Assay Automated Imaging Systems for UroVysion® FISH Analysis References Chapter 10: Cytopreparatory Techniques Background Materials and Methods Collection Processing Preparation Methods Discussion Conclusions and Recommendations References Chapter 11: Clinical Management Background Management of Negative for High Grade Urothelial Carcinoma (NHGUC) Management of Atypical Urothelial Cells Management of Suspicious/Positive for High Grade Urothelial Carcinoma Management of Low Grade Urothelial Neoplasms Management of Non-urothelial Tumors Management of the Unsatisfactory Specimen Management Conclusions References Afterword: The Paris System for Reporting Urinary Cytology Future Clinical and Research Needs for All Diagnostic Categories of The Paris System for Reporting Urinary Cytology Index

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