ENGLISH

Linkage Thermodynamics of Macromolecular Interactions

By Frederic M. Richards , David S. Eisenberg and Peter S. Kim (Eds.)

Book information

Publisher
Academic Press
Year
1998
ISBN
978-0-12-034251-8
ISSN
0065-3233
Open Library ID
OL7325332M
Language
english
Format
PDF
Filesize
23 MB (23945296 bytes)
Series
Advances in Protein Chemistry 51
Edition
1st
Pages
iii-x, 1-473\485
Library
duansci.com_Biology
Time added
2010-02-18 13:16:04

Description

This volume commemorates the 50th anniversary of the appearance in Volume 4 in 1948 of Dr. Jeffries Wyman's famous paper in which he "laid down" the foundations of linkage thermodynamics. Experts in this area contribute articles on the state-of-the-art of this important field and on new developments of the original theory. Among the topics covered in this volume are electrostatic contributions to molecular free energies in solution; site-specific analysis of mutational effects in proteins; allosteric transitions of the acetylcholine receptor; and deciphering the molecular code of hemoglobin allostery.

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