ENGLISH

Regulation of drug-metabolizing enzymes by sex-related hormones: clinical implications for transgender medicine

By An Le , Kai J Huang , Lauren R Cirrincione

Book information

Year
2022
Language
english
Format
PDF
Filesize
2 MB (1725636 bytes)
Pages
\11
Time added
2023-01-28 07:54:48

Description

Regulation of drug-„metabolizing enzymes by sex-„related hormones: clinical implications for transgender medicine Transgender people represent a diverse and growing population Testosterone and estrogen treatment are associated with increased quality of life among transgender adults Transgender people may undergo testosterone or estrogen treatment Investigators have not yet established the effect of testosterone or estrogen treatment on drug-metabolizing enzyme activit... CYP3A metabolizes several medication classes prescribed for transgender people, including anti-HIV agents, such as protease... CYP2B6 metabolizes several therapeutically used drugs prescribed for transgender adults, including the anti-HIV agent efavirenz CYP2C9 and 2C19 metabolize several important medications prescribed for transgender adults, including warfarin and clopidog... CYP2D6 metabolizes several psychotropic medications that may be prescribed for transgender adults CYP2E1 metabolizes medications taken by transgender people, including acetaminophen CYP1A2 metabolizes certain psychotropic medications that may be prescribed for transgender adults UGT metabolizes several medications prescribed for transgender adults, including lamotrigine Sex steroid-related activation of drug transporter protein expression or activity among transgender adults is not established Endogenous hormones may indirectly influence drug-metabolizing enzyme activity in transgender adults Adjunctive agents modify the extent of potential effects of estrogen treatment on drug-metabolizing enzymes for transgender... Nonhormonal sex-related and gender-related factors may also influence drug safety for transgender people Concluding remarks and future perspectives Declaration of interests Resources References

Similar books

Session C11: Ancient Cultural Landscapes in South Europe – their Ecological Setting and Evolution, Session C22: Gardeners from South America, Session S04: Agro-Pastoralism and Early Metallurgy Sessions, Session WS29: The Idea of Enclosure in Recent Iberian Prehistory, Session C88: Rhytmes et causalites des dynamiques de l'anthropisation en Europe entre 6500 ET 500 BC: Hypotheses socio-culturelles et/ou climatiques: Proceedings of the XV UISPP World Congress (Lisbon 4-9 September 2006) / Actes du XV Congrès Mondial (Lisbonne 4-9 Septembre 2006) Vol.36

2010 · PDF

THE BRITISH ARMY IN INDIA: ITS PRESERVATION BY AN APPROPRIATE CLOTHING, HOUSING, LOCATING, RECREATIVE EMPLOYMENT, AND HOPEFUL ENCOURAGEMENT OF THE TROOPS. with AN APPENDIX ON INDIA : THE CLIMATE OP ITS HILLS ; THE DEVELOPMENT OF ITS RESODRCBS, INDUSTRY, AND ARTS ; THE ADMINISTRATION OF JUSTICE ; THE BLACK ACT ; THE PROGRESS OF CHRISTIANITY ; THE TRAFFIC IN OPIUM ; THE VALUE OF INDIA ; PERMANENT CAUSES OF DISAFFECTION, AND OF THE RECENT REBELLION ; THE TRADITIONARY POLICY; MISGOVERNMENT BY NATIVE RULERS ; ANNEXATIONS OF THEIR TERRITORY, ETC.

1858 · PDF

Idries Shah 27 Books Collection : A Perfumed Scorpion, A Veiled Gazelle, Caravan of Dreams, Darkest England, Destination Mecca, Evenings with Idries Shah, Knowing How to Know, Learning How to Learn, Letters and Lectures of Idries Shah, Neglected aspects of Sufi study, Observations, Oriental Magic, Reflections, Seeker after Truth, Special Illumination, Special Problems in the study of Sufi ideas, Sufi thought and action, Tales of the Dervishes, The Dermis Probe, The Elephant in the Dark, The Englishman Handbook, Idries Shah Antology, The Magic Monastery, The natives are restless, wisdom of the Idiots PDF.

2022 · PDF

The travels of Capts. Lewis and Clarke from St. Louis, by way of the Missouri and Columbia rivers, to the Pacific ocean; performed in the years 1804, 1805 & 1806, by order of the government of the United States. Containing delineations of the manners, customs, religion, &c. of the Indians, comp. from various authentic sources, and original documents, and a summary of the Statistical view of the Indian nations, from the official communication of Meriwether Lewis. Illustrated with a map of the country, inhabited by the western tribes of Indians

1809 · PDF

Professional Linux kernel architecture ''Wrox programmer to programmer''--Cover. - ''What you are reading right now is the result of an evolution over more than seven years: After two years of writing, the first edition was published in German by Carl Hanser Verlag in 2003. It then described kernel 2.6.0. The test was used as a basis for the low-level design documentation for the EAL4+ security evaluation of Red Hat Enterprise Linux 5, requiring to update it to kernel 2.6.18 (if the EAL acronym does not mean anything to you, then Wikipedia is once more your friend). Hewlett-Packard sponsored the translation into English and has, thankfully, granted the rights to publish the result. Updates to kernel 2.6.24 were then performed specifically for this book''--P. ix

2008 · PDF