ENGLISH

Half a Century of Free Radical Chemistry

By Derek H. R. Barton , Shyamal I. Parekh

Book information

Publisher
Cambridge University Press
Year
1993
ISBN
052144005X, 9780521440059
Language
english
Format
DJVU
Filesize
929 kB (951076 bytes)
Series
Lezioni Lincee
Pages
176\173
Topic
Chemistry
Time added
2013-05-26 20:12:38

Description

This book describes the work of Nobel Laureate Derek Barton on the chemistry of organic free radicals, and the invention of new chemical reactions for use in the synthesis of biologically and economically important compounds. It begins with a mechanistic study of industrial significance on the pyrolysis of chlorinated alkanes. It continues with a theory on the biosynthesis of phenolate derived alkaloids involving phenolate radical coupling. The book then describes the work on nitrite photolysis (Barton reaction), which involved the invention of new radical chemistry leading to a simple synthesis of the important hormone, aldosterone. It also describes another new reaction extended to carboxlic acids that provides carbon, nitrogen, oxygen and other radicals under mild conditions. A final chapter summarizes recent applications of thiocarbonyl group derived radical reactions by other authors.

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