Enantioselective cobalt-catalysed transformations

Description

With a foreword from leading organic chemist Professor Paul Wender this book collects the major developments reported in the past thirty years in the field of enantioselective reactions promoted by chiral cobalt catalysts. Abstract: With a foreword from leading organic chemist Professor Paul Wender this book collects the major developments reported in the past thirty years in the field of enantioselective reactions promoted by chiral cobalt catalysts.  Read more... Content: Cover Enantioselective Cobalt-catalysed Transformations Foreword Abbreviations Contents Chapter 1 -- Enantioselective Cobalt-catalysed [2+1] Cycloadditions 1.1 Introduction 1.2 Cyclopropanations 1.2.1 Intermolecular Cyclopropanations 1.2.1.1 With Salen Cobalt Complexes 1.2.1.2 With Porphyrin Cobalt Complexes 1.2.1.3 With Other Cobalt Complexes 1.2.2 Intramolecular Cyclopropanations 1.3 Aziridinations and Epoxidations 1.3.1 Aziridinations 1.3.2 Epoxidations 1.4 Conclusions References Chapter 2 -- Other Enantioselective Cobalt-catalysed Cycloadditions 2.1 Enantioselective Cobalt-Catalysed (Hetero)-Diels-Alder Cycloadditions2.1.1 Diels-Alder Cycloadditions 2.1.2 Hetero-Diels-Alder Cycloadditions 2.2 Enantioselective Cobalt-Catalysed 1,3-Dipolar Cycloadditions 2.3 Enantioselective Cobalt-catalysed [2+2+2] and [2+2+1] Cycloadditions 2.3.1 [2+2+2] Cycloadditions 2.3.2 [2+2+1] Cycloadditions 2.4 Other Enantioselective Cobalt-Catalysed Cycloadditions 2.5 Conclusions References Chapter 3 -- Enantioselective Cobalt-catalysed Cyclisations Through Domino Reactions Conclusions References Chapter 4 -- Miscellaneous Enantioselective Cobalt-catalysed Cyclisations4.1 Using Salen Ligands 4.2 Using Biphosphine Ligands 4.3 Using Porphyrin Ligands 4.4 Using Other Ligands 4.5 Conclusions References Chapter 5 -- Synthesis of Chiral Acyclic Compounds Through Enantioselective Cobalt-catalysed Reduction Reactions 5.1 Reductions of Carbonyl Compounds and Derivatives 5.1.1 Borohydride Reductions 5.1.2 Hydrosilylations 5.1.3 Hydrogenations 5.2 Reductions of Alkenes 5.2.1 Reductions with Borane Derivatives 5.2.1.1 Borohydride Conjugate Reductions 5.2.1.2 Hydroborations 5.2.2 Hydrosilylations5.2.3 Hydrogenations 5.3 Conclusions References Chapter 6 -- Synthesis of Chiral Acyclic Compounds Through Enantioselective Cobalt-catalysed Ring-Opening Reactions 6.1 Hydrolytic and Alcoholytic Ring-Opening of Epoxides 6.2 Ring-Opening of Epoxides by Amines and Carbamates 6.3 Ring-Opening of Epoxides Through (Co)polymerisation 6.4 Conclusions References Chapter 7 -- Synthesis of Chiral Acyclic Compounds Through Enantioselective Cobalt-catalysed Michael and (Nitro)-Aldol Reactions 7.1 Michael Reactions 7.1.1 Michael Additions to [alpha],[beta]-Unsaturated Carbonyl Compounds and Derivatives7.1.2 Michael Additions to Nitroolefins 7.2 (Nitro)-Aldol Reactions 7.3 Conclusions References Chapter 8 - Synthesis of Chiral Acyclic Compounds Through Enantioselective Cobalt-catalysed 1,2-Nucleophilic Additions to Carbonyl Compounds and Derivatives Conclusions References Chapter 9 - Synthesis of Chiral Acyclic Compounds Through Enantioselective Cobalt-catalysed Cross-coupling Reactions Conclusions References Chapter 10 -- Synthesis of Chiral Acyclic Compounds Through Enantioselective Cobalt-catalysed Hydrovinylation Reactions