Regulation of carcinogenesis, angiogenesis and metastasis by the proprotein convertases (PCs) : a new potential strategy in cancer therapy
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Content: Preface.- Introduction.- List of Contributors.- 1. Discovery of the proprotein convertases and their inhibitors.- 2. Signalling pathways leading to furin expression in cancer.- 3. Pace4 gene expression in human ovarian cancer.- 4. Proprotein convertases in tumorigenesis, angiogenesis and metastasis.- 5. Proprotein convertases, Metalloproteases and tumor cell invasion.- 6. Modulation of integrin function by endoproteolytic processing: Role in tumor progression.- 7. Growth factors: to cleave or not to cleave.- 8. Evaluation of anti-proprotein convertase activity of diterpene andrographolid derived products.
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