ENGLISH

New Approaches to Drug Discovery

Book information

Publisher
Springer
Year
2016
ISBN
3319289128, 9783319289120, 9783319289144
DOI
10.1007/978-3-319-28914-4
ISSN
0171-2004
Language
english
Format
PDF
Filesize
9 MB (9167899 bytes)
Series
Handbook of Experimental Pharmacology 232
Edition
1
Pages
C,VIII,341\335
Orientation
portrait
Paginated
yes
Scanned
no
Time added
2016-04-26 07:07:47

Description

In depth insights into drug discovery and early drug development Latest technologies of target discovery and lead generation New approaches to transfer drug candidates to clinical development This volume gives an overview of state of the art technologies and future developments in the field of preclinical pharmaceutical research. A balanced mix of experts from academia and industry give insight in selected new developments in the drug discovery pathway. The topics cover the different parts of the drug discovery process, starting with new developments in the target identification and validation area. The lead generation part as a next step focuses on the requirements and technologies to identify new small molecules as lead compounds for further optimization; in a second section the technologies to identify biologics as leads are addressed. The final part focuses on the pharmacological models and technologies to characterize new compounds and the impact of biomarkers to facilitate the transfer of drug candidates into the development phase. Topics Pharmacology / Toxicology Drug Safety and Pharmacovigilance Medical Biochemistry Metabolomics

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