ENGLISH

Tumor-Induced Immune Suppression: Mechanisms and Therapeutic Reversal

By Dmitry I. Gabrilovich , Andy Hurwitz

Book information

Publisher
Springer
Year
2007
ISBN
0387691170, 9780387691176, 9780387691183
LCC
QR188.6 .T8645 2008
Open Library ID
OL20640186M
Language
english
Format
PDF
Filesize
4 MB (3964146 bytes)
Edition
1
Pages
304\304
Topic
Medicine Therapy
Time added
2010-08-30 15:18:36

Description

There is now a pressing need to discuss the already described and newly emerging mechanisms to see how they can be put together in more or less cohesive structure and how they can help to improve immune response to tumors. This monograph will, for the first time, present a comprehensive overview of different mechanisms of immune dysfunction in cancer as well as therapeutic approaches to their correction. It will discuss a number of new mechanisms that have never been discussed in a monograph before: T-cell inhibitory molecules, regulatory tolerogenic DCs, and signaling pathways in antigen-presenting cells involved in T-cell tolerance.

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