Periparturient Diseases of Dairy Cows: A Systems Biology Approach

Description

This book summarizes the results achieved so far by application of various biological systems (including genomics, transcriptomics, proteomics, and metabolomics) involved in the pathomechanisms and early diagnosis of periparturient diseases as specific biomarkers of disease in cattle. These emerging technologies help to extensively enhance our understanding of the etiology and pathogenesis of periparturient diseases of transition dairy cows. The book includes a chapter dedicated to ‘omics’ sciences and one that discusses the myths established in animal and veterinary sciences in recent decades and emerging, new paradigms. The diseases discussed include metritis, mastitis, laminitis, ketosis, rumen acidosis, periparturient immunosuppression, gastrointestinal microbiota and their involvement in disease, infertility, fatty liver, milk fever, and retained placenta. This book is intended for academics, veterinarians, animal nutritionists, researchers, and graduate students working in the field of ‘omics sciences’ with a special interest in dairy cattle health. Front Matter ....Pages i-xiv What Are Omics Sciences? (Mario Vailati-Riboni, Valentino Palombo, Juan J. Loor)....Pages 1-7 Demystifying the Myths: Switching Paradigms from Reductionism to Systems Veterinary in Approaching Transition Dairy Cow Diseases (Burim N. Ametaj)....Pages 9-29 An Omics Approach to Transition Cow Immunity (Emily F. Eckel, Burim N. Ametaj)....Pages 31-50 Systems Biology and Ruminal Acidosis (Morteza H. Ghaffari, Ehsan Khafipour, Michael A. Steele)....Pages 51-69 Cattle Gastrointestinal Tract Microbiota in Health and Disease (André Luiz Garcia Dias, Burim N. Ametaj)....Pages 71-91 A Systems Biology Approach to Dairy Cattle Subfertility and Infertility (Fabrizio Ceciliani, Domenico Vecchio, Esterina De Carlo, Alessandra Martucciello, Cristina Lecchi)....Pages 93-119 Retained Placenta: A Systems Veterinary Approach (Elda Dervishi, Burim N. Ametaj)....Pages 121-137 Omic Approaches to a Better Understanding of Mastitis in Dairy Cows (Manikhandan Mudaliar, Funmilola Clara Thomas, Peter David Eckersall)....Pages 139-183 Laminitis: A Multisystems Veterinary Perspective with Omics Technologies (Richard R. E. Uwiera, Ashley F. Egyedy, Burim N. Ametaj)....Pages 185-200 Ketosis Under a Systems Veterinary Medicine Perspective (Guanshi Zhang, Burim N. Ametaj)....Pages 201-222 The Omics Side of Fatty Liver: A Holistic Approach for a Commonly Occurring Peripartal Disease (Mario Vailati-Riboni, Valentino Palombo, Juan J. Loor)....Pages 223-246 Milk Fever: Reductionist Versus Systems Veterinary Approach (Elda Dervishi, Burim N. Ametaj)....Pages 247-266 Back Matter ....Pages 267-276