Lung Transplantation

Description

Clinical lung transplantation has seen an early start within the history of solid organ trans­ plantation, marked by the 1963 first lung transplant by James D. Hardy. This was prompted by the seemingly easy way of joining the transplanted organ to the recipient by me ans of a few well-defined anastomoses, i.e. bronchus, pulmonary artery and pulmonary vein carry­ ing left atrial cuff. The following decade thus witnessed a number of such mostly unilateral lung transplants in several centres, in Germany represented by the two only lung transplants performed by E. S. Bücherl, then at the Neukölln City Hospital in Berlin in 1969. As with most other such attempts these two patients suffered early and lethai graft failure. There was only one single lung transplant patient who lived up to ten months after the transplant at Gent, Belgium, having been operated on by Derom in 1969. The alm ost universal failure during this initial phase was attributed to bronchial anasto­ motic insufficiency, pulmonary infection of either the transplanted lung or the left-in-place contralateral lung and a far-reaching lack of knowledge how to cope with transplant rejec­ tion. In the early 1970s it had become gene rally accepted that lung transplantation could not be performed successfully. Front Matter....Pages I-VII Single versus bilateral lung transplantation....Pages 1-8 Rejection and infection after lung transplantation....Pages 9-24 Management of bronchial complications in lung transplantation....Pages 25-32 Lung transplantation in cystic fibrosis....Pages 33-43 Lung transplantation for acute pulmonary failure....Pages 45-50 Lung and heart-lung transplantation with direct bronchial artery revascularization....Pages 51-69