ENGLISH

LC-MS in Drug Bioanalysis

By Q. Alan Xu , Aimin Tan , Nadine Boudreau , Ann Lévesque (auth.) , Timothy L. Madden (eds.)

Book information

Publisher
Springer US
Year
2012
ISBN
1461438276, 9781461438274
DOI
10.1007/978-1-4614-3828-1
LCC
2012940715
Google Books ID
HC3mwHLqTgwC
Language
english
Format
PDF
Filesize
7 MB (7577045 bytes)
Edition
1
Pages
472\483
Orientation
yes
Paginated
yes
Scanned
portrait
Time added
2013-07-24 03:46:30
Mass Spectrometry; Analytical Chemistry; Pharmacol

Description

Clinical pharmacology plays an important role in today’s medicine. Due to the high sensitivity, selectivity, and affordability of a mass spectrometer (MS), the high performance liquid chromatography – mass spectrometry (LC-MS) analytical technique is widely used in the determination of drugs in human biological matrixes for clinical pharmacology. Specifically, LC-MS is used to analyze: anticancer drugs antidementia drugs antidepressant drugs antiepileptic drugs antifundal drug antimicrobial drugs antipsychotic drugs antiretroviral drugs anxiolytic/hypnotic drugs cardiac drugs drugs for addiction immunosuppressant drugs mood stabilizer drugs This book will primarily cover the various methods of validation for LC-MS techniques and applications used in modern clinical pharmacology.

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