ENGLISH

Alcohol and Cancer

By Philip J. Brooks PhD (auth.) , Samir Zakhari , Vasilis Vasiliou , Q. Max Guo (eds.)

Book information

Publisher
Springer-Verlag New York
Year
2011
ISBN
1461400392, 9781461400394, 9781461400400
DOI
10.1007/978-1-4614-0040-0
Google Books ID
1uKmNJ8npqIC
Open Library ID
OL25155295M
Language
english
Format
PDF
Filesize
6 MB (5926312 bytes)
Edition
1
Pages
243\260
Orientation
yes
Scanned
no
Time added
2012-02-14 18:00:00
Cancer Research; Pharmacology/Toxicology

Description

The World Health Organization has identified chronic alcohol consumption as one of the top ten risk factors for worldwide burden of disease. The International Agency for Research on Cancer has identified alcohol as carcinogenic to humans, including cancers of the upper aerodigestive tract, colon, liver and breast. Alcohol’s actions may be direct e.g. effects on retinoic acid and one-carbon metabolism, or indirect, through metabolites such as acetaldehyde and reactive oxygen species or through various signaling pathways that influence cell cycle and apoptosis that may contribute to carcinogenesis. This volume reviews the state of the art in alcohol-related cancer research in ten chapters.

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