ENGLISH

Thrombin: Physiology and Disease

By Enrico Di Cera* , Andras Gruber (auth.) , Michael E. Maragoudakis , Nikos E. Tsopanoglou (eds.)

Book information

Publisher
Springer-Verlag New York
Year
2009
ISBN
0387096361, 9780387096360
DOI
10.1007/978-0-387-09637-7
LCC
TK5103.59 .S45
Open Library ID
OL4415989M
Language
english
Format
PDF
Filesize
2 MB (2113114 bytes)
Edition
1
Pages
266\272
Orientation
no
Scanned
no
Time added
2011-06-04 13:46:07
Cancer Research; Pharmacology/Toxicology; Biochemigeneral; Epidemiology

Description

It has become increasingly evident in recent years that, apart from the key role that thrombin plays in the blood coagulation cascade, thrombin also elicits cellular actions via the activation of proteinase-activated receptors, which are present in many cell types. These effects of thrombin are seen in a variety of physiological as well as pathological phenomena, including vascular development and physiology, tumor progression and metastasis, neuronal functions, inflammation, angiogenesis. Thrombin: Physiology and Disease, edited by Michael E. Maragoudakis and Nikos E. Tsopanoglou, emphasizes the new developments in this important field of research and provides the basis for translating these findings into therapeutic targets."

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