Diagnostic Pathology: Cytopathology second ed Dina R Mody MD, Savitri Krishnamurthy MD, Michael J. Thrall MD

Description

Cover Copyright Dedications Contributing Authors Preface Acknowledgments Sections Contents Gynecologic Cytopathology: Overview Pap Test and Cervical Cancer Screening: History and Reporting Terminology Cytopreparation, Instrumentation, and Automated Screening in Gynecologic Cytology Specimen Adequacy in Cervicovaginal Cytology Gynecologic Cytopathology: Benign and Infectious Conditions Normal Pap Test Infectious and Other Organisms in Pap Tests Nonneoplastic Findings, Mimics, and Artifacts Gynecologic Cytopathology: Squamous Cell Abnormalities and Mimics Low-Grade Squamous Intraepithelial Lesion and Mimics High-Grade Squamous Intraepithelial Lesion and Mimics Atypical Squamous Cells of Undetermined Significance Atypical Squamous Cells, Cannot Rule Out High-Grade Squamous Intraepithelial Lesion Squamous Cell Carcinoma of Cervix, Variants and Mimics Gynecologic Cytopathology: Glandular Cell Abnormalities and Mimics Endocervical Adenocarcinoma In Situ, Variants and Mimics Adenocarcinoma, Minimal Deviation Endometrial Cancers: Usual Types, Variants, and Mimics Atypical Glandular Cells: Endocervicals, Endometrials, and Glandulars, NOS Endometrial Cells in Pap Test and Glandular Cells Status Post Hysterectomy Gynecologic Cytopathology: Extrauterine Carcinomas and Other Malignancies of Female Genital Tract Extrauterine Carcinomas and Presentations in Cervicovaginal Cytology Small Cell Neuroendocrine Carcinoma of Cervix Other Uncommon Malignancies in Cervicovaginal Cytology Gynecologic Cytopathology: Molecular Testing in Gynecologic Cytology HPV and Other Molecular Testing in Gynecologic Cytology Gynecologic Cytopathology: Directly Sampled Endometrial Cytology Directly Sampled Endometrial Cytology Gynecologic Cytopathology: Anal Cytology Anal Cytology Exfoliative Cytopathology: Respiratory Tract Including Lung FNAs Specimen Types in Respiratory Cytology and Adequacy Criteria Benign and Reactive Changes Pneumocystis Pneumonia and Mimics Fungal Organisms in Respiratory Cytology Parasitic Organisms in Respiratory Cytology Viral Infections (Cytomegalovirus, Herpesvirus, and Others) Mycobacteria and Other Bacterial Infections Sarcoidosis and Other Immune-Related Conditions Pulmonary Alveolar Proteinosis and Mimics Miscellaneous Findings Including Contaminants Adenocarcinoma Squamous Cell Carcinoma Small Cell Carcinoma Large Cell Neuroendocrine Carcinoma Carcinoid and Atypical Carcinoid Rare Benign and Low Malignant Potential Tumors Rare Malignant Tumors Pulmonary Lymphoma Exfoliative Cytopathology: Gastrointestinal Tract Specimen Types in Gastrointestinal Cytology and Normal Cellular Components Parasitic Infections Viral Infections Esophagitis and Barrett Esophagus Esophageal Adenocarcinoma Esophageal Squamous Cell Carcinoma Gastritis and Intestinal Metaplasia Gastric Adenocarcinoma Gastric Lymphoma Ampulla/Bile Duct/Pancreatic Duct Reactive Changes Colorectal Adenoma/Carcinoma Neuroendocrine Tumor/Carcinoma Spindle Cell Neoplasms of Gastrointestinal Tract, Including Gastrointestinal Stromal Tumors Exfoliative Cytopathology: Cerebrospinal Fluid Normal Cerebrospinal Fluid and Contamination by Normal Elements Infectious Meningitis Aseptic and Mollaret Meningitis Subarachnoid Hemorrhage Neurodegenerative Diseases Primary Brain Tumors Leukemia and Lymphoma Metastasis in CSF Exfoliative Cytopathology: Pleural, Peritoneal, Pericardial, and Pelvic Fluid and Washings Normal Cellular Components and Reactive Mesothelial Proliferations Infectious Conditions Autoimmune Diseases Malignant Effusion, Mesothelioma Lymphoid Effusions and Lymphomas Primary Effusion Lymphoma Endometriosis and Endosalpingiosis Ovarian Neoplasms Immunocytochemistry, Histochemistry, and Other Ancillary Techniques Exfoliative Cytopathology: Urinary Cytology Normal Urinary Cytology, Specimen Types, and Reporting Terminology Ileal Conduit Specimens Noninfectious Benign Conditions Infectious Benign Conditions Reactive Urothelial Changes Low-Grade Urothelial Lesions High-Grade Urothelial Dysplasia/Carcinoma/Carcinoma In Situ Squamous Cell Carcinoma of Urinary Bladder Adenocarcinoma of Urinary Bladder Other Malignancies in Urinary Cytology Renal Pelvic Cytology Ancillary Testing, UroVysion, and Others Fine-Needle Aspiration, Superficial: Overview Superficial Aspiration Technique Fine-Needle Aspiration, Superficial: Thyroid Gland Ultrasound-Guided Thyroid Fine-Needle Aspiration Thyroid Fine-Needle Aspiration Reporting Terminology and Specimen Adequacy Adenomatous (Benign Follicular) Nodule Chronic Lymphocytic/Hashimoto Thyroiditis Granulomatous Thyroiditis Graves Disease/Diffuse Toxic Goiter Pigmented Thyroid Lesions and Crystals Atypia of Undetermined Significance/Follicular Lesion of Undertermined Significance Follicular Neoplasm/Suspicious for a Follicular Neoplasm Follicular Neoplasm, Hürthle Cell (Oncocytic) Type Papillary Thyroid Carcinoma, Classic Variant Medullary Thyroid Carcinoma Poorly Differentiated Thyroid Carcinoma Anaplastic Thyroid Carcinoma Thyroid Lymphoma Metastatic Carcinoma to Thyroid Other Nonneoplastic and Neoplastic Thyroid Lesions Encountered on Thyroid FNA Fine-Needle Aspiration, Superficial: Parathyroid Gland Parathyroid Cyst, Adenoma, and Carcinoma Fine-Needle Aspiration, Superficial: Lymph Nodes Indications for Aspiration and Techniques FNA Sample Prep and Triage in Evaluating Suspected Lymphoma Inflammatory and Reactive Lymphoid Hyperplasia Granulomatous Lymphadenitis, Infectious and Sarcoid Rosai-Dorfman Disease Metastatic Malignancies (Carcinoma, Melanoma) HPV-Positive Head and Neck Squamous Cell Carcinoma Small Lymphocytic Lymphoma Lymphoplasmacytic Lymphoma Mantle Cell Lymphoma Nodal Marginal Zone Lymphoma Follicular Lymphoma Burkitt Lymphoma Large B-Cell Lymphoma Plasmacytoma Mediastinal Large B-Cell Lymphoma Plasmablastic Lymphoma Peripheral T-Cell Lymphoma Mycosis Fungoides Angioimmunoblastic Lymphoma ALK(+) Anaplastic Large Cell Lymphoma T-Cell Lymphoblastic Lymphoma Nodular Lymphocyte-Predominant Hodgkin Lymphoma Classical Hodgkin Lymphoma Fine-Needle Aspiration, Superficial: Salivary Gland Approach to Interpretation of Salivary Gland Aspiration Biopsies and Reporting Terminology (Milan System) Normal Salivary Gland and Sialadenitis on Aspiration Cysts Pleomorphic Adenoma Warthin Tumor Myoepithelioma Oncocytoma, Salivary Gland Adenoid Cystic Carcinoma Acinic Cell Carcinoma Mucoepidermoid Carcinoma Basaloid Neoplasms, Benign and Malignant Carcinoma Ex Pleomorphic Adenoma Adenocarcinoma, Not Otherwise Specified Polymorphous Low-Grade Adenocarcinoma Salivary Duct Carcinoma Secretory Carcinoma Myoepithelial Carcinoma Cribriform Adenocarcinoma Metastatic Carcinoma Primary and Metastatic Nonepithelial Tumors Fine-Needle Aspiration, Superficial: Breast Role of Fine-Needle Aspiration of Breast, Techniques and Triple Test Inflammatory and Granulomatous Conditions Fat Necrosis Nonproliferative and Proliferative Changes in Breast Radial Scar/Complex Sclerosing Lesion Gynecomastia Mucocele-Like Lesion Fibroadenoma Granular Cell Tumor of Breast Papillary Neoplasms Myofibroblastoma, Mammary Ductal Carcinoma and Variants of Invasive Mammary Carcinoma Lobular Carcinoma Phyllodes Tumor Angiosarcoma and Other Sarcomas Lymphomas and Metastatic Tumors Cytology Specimens for Risk Assessment of Breast Cancer Fine-Needle Aspiration, Superficial: Skin and Subcutaneous Cytology Cutaneous and Adnexal Cytology Fine-Needle Aspiration, Deep Organs and Tissues: Overview Techniques and Modalities of Deep Aspiration Biopsies Fine-Needle Aspiration, Deep Organs and Tissues: Mediastinum Anatomic Compartments and Constituent Tumors Mediastinal Cysts and Inflammatory Lesions Thymoma Thymic Carcinoma Germ Cell Tumors Neurogenic Tumors Metastatic Tumors of Mediastinum Fine-Needle Aspiration, Deep Organs and Tissues: Liver Cytology of Normal Liver Inflammatory and Infectious Conditions of Liver Hepatocellular Adenoma Focal Nodular Hyperplasia Hemangioma, Liver Hepatocellular Carcinoma Hepatoblastoma Liver Metastasis Fine-Needle Aspiration, Deep Organs and Tissues: Kidney Cytology of Normal Kidney Renal Cysts Angiomyolipoma Oncocytoma, Kidney Metanephric Adenoma Metanephric Stromal Tumor Xanthogranulomatous Pyelonephritis/Malakoplakia Clear Cell Renal Cell Carcinoma Papillary Renal Cell Carcinoma Clear Cell Papillary Renal Cell Carcinoma Chromophobe Renal Cell Carcinoma Collecting Duct Carcinoma Renal Medullary Carcinoma Mucinous Tubular and Spindle Cell Carcinoma of Kidney Carcinoid Tumor Primary Renal Sarcomas in Adults Renal Lymphomas Nephroblastoma (Wilms Tumor) Clear Cell Sarcoma of Kidney Congenital Mesoblastic Nephroma Rhabdoid Tumor of Kidney Metastatic Tumors to Kidney Urothelial Carcinoma Fine-Needle Aspiration, Deep Organs and Tissues: Adrenal Gland Cytology of Normal Adrenal Gland Adrenal Cortical Adenoma Metastatic Tumors to Adrenal Gland Pheochromocytoma Fine-Needle Aspiration, Deep Organs and Tissues: Pancreas Cytology of Normal Pancreas Pancreatic Cytology Reporting Terminology, Cyst Evaluation Pancreatitis Lymphoepithelial Cyst of Pancreas Intra- and Peripancreatic Splenules Serous Microcystic Adenoma Mucinous Cystic Neoplasm Intraductal Papillary Mucinous Neoplasm Solid Pseudopapillary Neoplasm Pancreatic Neuroendocrine Tumor Pancreatic Ductal Adenocarcinoma Unusual Variants of Ductal Carcinoma Acinar Cell Carcinoma Lymphoma and Secondary Tumors of Pancreas Fine-Needle Aspiration, Deep Organs and Tissues: Bone Approach to Cytologic/Small Biopsy Diagnosis of Primary Bone Tumors Chondromas of Bone and Soft Tissue Chondroblastoma Giant Cell Tumor Osteoblastoma Adamantinoma Langerhans Cell Histiocytosis Chordoma Osteosarcoma Chondrosarcoma Ewing Sarcoma Bone Lymphoma Metastatic Tumors of the Bone Fine-Needle Aspiration, Deep Organs and Tissues: Soft Tissue Approach to Cytologic/Small Biopsy Diagnosis of Primary Soft Tissue Lesions Benign Adipose Tissue Tumors Liposarcoma Fibrosarcoma Myofibroblastoma Low-Grade Myofibroblastic Sarcoma Giant Cell Tumor of Tendon Sheath Undifferentiated Pleomorphic Sarcoma Smooth Muscle Tumors Skeletal Muscle Tumors Hemangioma, Soft Tissue Epithelioid Hemangioendothelioma Angiosarcoma Other Reactive and Neoplastic Soft Tissue Entities Mesenchymal Chondrosarcoma Solitary Fibrous Tumor Intramuscular Myxoma Synovial Sarcoma Epithelioid Sarcoma Alveolar Soft Part Sarcoma Clear Cell Sarcoma of Soft Tissue Desmoplastic Small Round Cell Tumor Fine-Needle Aspiration, Deep Organs and Tissues: Ophthalmic and Neuropathology Approach to Ophthalmic Cytology Ophthalmic Cytopathology, Infectious Ophthalmic Cytopathology, Neoplastic Neuropathology Squash Preparations, Infectious Neuropathology Squash Preparations, Glial Neoplasms Neuropathology Squash Preparations, Nonglial Neoplasms Management and Ancillary Testing: Cytopreparatory and Quality Management Cytopreparatory Techniques and Instrumentation in Nongynecologic Cytology Quality Improvement and Laboratory Management for Cytopathology Management and Ancillary Testing: Ancillary Testing Immunocytochemistry Molecular Techniques Index Copyright Title Page Dedication Contents Chapter 1: ‘I’m thinking’ – Oh, but are you? Chapter 2: Renegade perception Chapter 3: The Pushbacker sting Chapter 4: ‘Covid’: The calculated catastrophe Chapter 5: There is no ‘virus’ Chapter 6: Sequence of deceit Chapter 7: War on your mind Chapter 8: ‘Reframing’ insanity Chapter 9: We must have it? So what is it? Chapter 10: Human 2.0 Chapter 11: Who controls the Cult? Chapter 12: Escaping Wetiko Postscript Appendix: Cowan-Kaufman-Morell Statement on Virus Isolation Bibliography Index