ENGLISH

Autophagy Regulation of Innate Immunity

By Jun Cui

Book information

Publisher
Springer Singapore
Year
2019
ISBN
978-981-15-0605-5, 978-981-15-0606-2
Language
english
Format
PDF
Filesize
4 MB (4342344 bytes)
Series
Advances in Experimental Medicine and Biology 1209
Edition
1st ed. 2019
Pages
IX, 203\210
Time added
2020-02-08 04:43:10
Biomedicine; Immunology; Cell Biology; Molecular M

Description

This book discusses novel concepts and discoveries concerning the regulation of innate immunity by autophagy and autophagy-related proteins. In the past decade, there have been major advances in our understanding of the molecular mechanisms of autophagy and its physiological functions. This book highlights emerging studies on the underlying mechanisms of autophagy regulation of innate immunity, including inflammation, antiviral immunity and anti-bacterial responses and the signaling pathways that prompt or inhibit the initiation and progression of related diseases. It also offers new ideas and strategies for future drugs based on manipulating autophagy, especially selective autophagy mediated by cargo receptors. Providing a comprehensive overview of the autophagy regulation of innate immunity, it is a valuable resource for graduate students and researchers in the fields of immunology, cell biology and translational medicine. Front Matter ....Pages i-ix Introduction (Jun Cui)....Pages 1-6 Autophagy Regulation of Mammalian Immune Cells (Wenzhuo He, Wenjing Xiong, Xiaojun Xia)....Pages 7-22 Autophagy in Plant Immunity (Hong-Yun Zeng, Ping Zheng, Ling-Yan Wang, He-Nan Bao, Sunil Kumar Sahu, Nan Yao)....Pages 23-41 Autophagy Regulation of Bacterial Pathogen Invasion (Yuqing Lei, Huihui Li, Kefeng Lu)....Pages 43-54 Autophagy and Viral Infection (Jingrong Mao, Eena Lin, Lian He, Jiaming Yu, Peng Tan, Yubin Zhou)....Pages 55-78 The Interplay Between Pattern Recognition Receptors and Autophagy in Inflammation (Yun Zhu, Jian Deng, Mei-Ling Nan, Jing Zhang, Akinkunmi Okekunle, Jiang-Yuan Li et al.)....Pages 79-108 Regulation of Inflammasome by Autophagy (Tao Liu)....Pages 109-123 The Cross-Regulation Between Autophagy and Type I Interferon Signaling in Host Defense (Shouheng Jin)....Pages 125-144 Selective Autophagy Regulates Innate Immunity Through Cargo Receptor Network (Yaoxing Wu, Jun Cui)....Pages 145-166 Autophagy and Immune-Related Diseases (Peng Tan, Youqiong Ye, Jingrong Mao, Lian He)....Pages 167-179 Targeting Autophagy with Small-Molecule Modulators in Immune-Related Diseases (Lan Zhang, Bo Liu)....Pages 181-203

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