Neuroprogression in Psychiatric Disorders
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In this volume, international experts critically review cutting-edge advances in neuroprogression research. The relevance of these findings to psychiatric and neurological disorders is clarified. Potential etiopathological mechanisms of neuroprogression are described in detail. Special emphasis is placed on the role of the immune system in stress and stress-related disorders and brain-immune interactions. The epigenetic consequences of adverse experiences in early childhood, which may prelude major psychiatric disorders, are also considered. Recent research has not only provided evidence of neuroprogression in psychiatric and neurological disorders, but has shown that pharmacologic interventions have the potential to arrest this process. Advances in testing and imaging will lead to timely diagnosis and earlier treatment. Identification of neurological mechanisms alongside (epi-)genetic vulnerability markers will create truly personalized treatment programs. This book is a valuable resource for everyone who wishes to gain insight into the essential features of the neuroprogressive course of major psychiatric and neurological disorders. In particular, psychiatrists, neuroscientists and neurologists ¬ as well as immunologists, pharmacologists and molecular biologists - will find very informative chapters of direct relevance to their field. I Preliminaries Halaris A, Leonard BE (eds): Neuroprogression in Psychiatric Disorders. Mod Trends Pharmacopsychiatry. Basel, Karger, 2017, vol 31, pp I-VIII (DOI:10.1159/000475445) 1 Neuroprogression in Schizophrenia and Psychotic Disorders: The Possible Role of Inflammation Müller N. Halaris A, Leonard BE (eds): Neuroprogression in Psychiatric Disorders. Mod Trends Pharmacopsychiatry. Basel, Karger, 2017, vol 31, pp 1-9 (DOI:10.1159/000470802) 10 The Link between Refractoriness and Neuroprogression in Treatment-Resistant Bipolar Disorder Bauer I.E. · Soares J.C. · Selek S. · Meyer T.D. Halaris A, Leonard BE (eds): Neuroprogression in Psychiatric Disorders. Mod Trends Pharmacopsychiatry. Basel, Karger, 2017, vol 31, pp 10-26 (DOI:10.1159/000470803) 27 Neuroprogression and Immune Activation in Major Depressive Disorder Meyer J.H. Halaris A, Leonard BE (eds): Neuroprogression in Psychiatric Disorders. Mod Trends Pharmacopsychiatry. Basel, Karger, 2017, vol 31, pp 27-36 (DOI:10.1159/000470804) 37 Inflammation Effects on Glutamate as a Pathway to Neuroprogression in Mood Disorders Haroon E. · Miller A.H. Halaris A, Leonard BE (eds): Neuroprogression in Psychiatric Disorders. Mod Trends Pharmacopsychiatry. Basel, Karger, 2017, vol 31, pp 37-55 (DOI:10.1159/000470805) 56 Major Depression as a Neuroprogressive Prelude to Dementia: What Is the Evidence? Leonard B.E. Halaris A, Leonard BE (eds): Neuroprogression in Psychiatric Disorders. Mod Trends Pharmacopsychiatry. Basel, Karger, 2017, vol 31, pp 56-66 (DOI:10.1159/000470807) 67 Innate Immune Memory: Implications for Microglial Function and Neuroprogression Salam A.P. · Pariante C.M. · Zunszain P. Halaris A, Leonard BE (eds): Neuroprogression in Psychiatric Disorders. Mod Trends Pharmacopsychiatry. Basel, Karger, 2017, vol 31, pp 67-78 (DOI:10.1159/000470808) 79 Inflammatory and Innate Immune Markers of Neuroprogression in Depressed and Teenage Suicide Brain Pandey G.N. Halaris A, Leonard BE (eds): Neuroprogression in Psychiatric Disorders. Mod Trends Pharmacopsychiatry. Basel, Karger, 2017, vol 31, pp 79-95 (DOI:10.1159/000470809) 96 Towards an Integrated View of Early Molecular Changes Underlying Vulnerability to Social Stress in Psychosis Barron H. · Hafizi S. · Mizrahi R. Halaris A, Leonard BE (eds): Neuroprogression in Psychiatric Disorders. Mod Trends Pharmacopsychiatry. Basel, Karger, 2017, vol 31, pp 96-106 (DOI:10.1159/000470810) 107 Neurodegeneration, Neuroregeneration, and Neuroprotection in Psychiatric Disorders Tang S.W. · Helmeste D.M. · Leonard B.E. Halaris A, Leonard BE (eds): Neuroprogression in Psychiatric Disorders. Mod Trends Pharmacopsychiatry. Basel, Karger, 2017, vol 31, pp 107-123 (DOI:10.1159/000470811) 124 The Contribution of Adult Hippocampal Neurogenesis to the Progression of Psychiatric Disorders Kohman R.A. · Rhodes J.S. Halaris A, Leonard BE (eds): Neuroprogression in Psychiatric Disorders. Mod Trends Pharmacopsychiatry. Basel, Karger, 2017, vol 31, pp 124-151 (DOI:10.1159/000470812) 152 The Brain-Gut Axis Contributes to Neuroprogression in Stress-Related Disorders Rea K. · Dinan T.G. · Cryan J.F. Halaris A, Leonard BE (eds): Neuroprogression in Psychiatric Disorders. Mod Trends Pharmacopsychiatry. Basel, Karger, 2017, vol 31, pp 152-161 (DOI:10.1159/000470813) 162 Pharmacological and Nonpharmacological Interventions to Arrest Neuroprogression in Psychiatric Disorders Boufidou F. · Halaris A. Halaris A, Leonard BE (eds): Neuroprogression in Psychiatric Disorders. Mod Trends Pharmacopsychiatry. Basel, Karger, 2017, vol 31, pp 162-176 (DOI:10.1159/000470814) 177 Author Index Halaris A, Leonard BE (eds): Neuroprogression in Psychiatric Disorders. Mod Trends Pharmacopsychiatry. Basel, Karger, 2017, vol 31, pp 177 (DOI:10.1159/000475446) 178 Subject Index Halaris A, Leonard BE (eds): Neuroprogression in Psychiatric Disorders. Mod Trends Pharmacopsychiatry. Basel, Karger, 2017, vol 31, pp 178-182 (DOI:10.1159/000475447)
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