Stem Cell Microenvironments and Beyond

Description

This book discusses the main stem cell niches under distinct pathophysiological conditions. The role of tissue microenvironments in stem cell regulation, as well as modern methodologies and new techniques for the identification and characterization of stem cell niches, are discussed by leading experts in the field. Chapters describe the major components of various stem cell microenvironments, such as cellular components, soluble factors, cell-cell interactions, extra-cellular matrix proteins, and physical forces. Stem Cell Microenvironments and Beyond is part of the highly successful Advances in Experimental Medicine and Biology series. It is essential reading for graduate students and researchers in the field of stem cells or cell biology as well as clinicians. Front Matter ....Pages i-xi Stem Cell Microenvironments and Beyond (Alexander Birbrair)....Pages 1-3 The Bone Marrow Microenvironment for Hematopoietic Stem Cells (Daniel Lucas)....Pages 5-18 Leukemia Stem Cells Microenvironment (Yoko Tabe, Marina Konopleva)....Pages 19-32 Developmental HSC Microenvironments: Lessons from Zebrafish (Sara Nik, Joshua T. Weinreb, Teresa V. Bowman)....Pages 33-53 Spinal Cord Stem Cells In Their Microenvironment: The Ependyma as a Stem Cell Niche (Nicolás Marichal, Cecilia Reali, Omar Trujillo-Cenóz, Raúl E. Russo)....Pages 55-79 Being a Neural Stem Cell: A Matter of Character But Defined by the Microenvironment (Evangelia Andreopoulou, Asterios Arampatzis, Melina Patsoni, Ilias Kazanis)....Pages 81-118 Glioblastoma Stem Cells and Their Microenvironment (Anirudh Sattiraju, Kiran Kumar Solingapuram Sai, Akiva Mintz)....Pages 119-140 Plasticity of the Muscle Stem Cell Microenvironment (Ivana Dinulovic, Regula Furrer, Christoph Handschin)....Pages 141-169 The Macula Flava of the Human Vocal Fold as a Stem Cell Microenvironment (Kiminori Sato)....Pages 171-186 Oesophageal Stem Cells and Cancer (Maria P. Alcolea)....Pages 187-206 Oral Cancer Stem Cells Microenvironment (Prajna Paramita Naik, Prashanta Kumar Panda, Sujit K. Bhutia)....Pages 207-233 Fetal Membranes-Derived Stem Cells Microenvironment (Phelipe Oliveira Favaron, Maria Angelica Miglino)....Pages 235-244 Current Technologies Based on the Knowledge of the Stem Cells Microenvironments (Damia Mawad, Gemma Figtree, Carmine Gentile)....Pages 245-262 Back Matter ....Pages 263-270