Asymmetric Synthesis II: More Methods and Applications

Description

Continuing the proven and successful concept of the well-received textbook "Asymmetric Synthesis - The Essentials", this is a brief and timely update on the latest developments in asymmetric synthesis and selected applications in natural product synthesis, chemical industry and materials science. As such, it covers a broad range of topics in all important areas, including metal catalysis, organocatalysis, physical organic chemistry, and analytical chemistry. Each contribution is similarly structured, while the short biographies of the experts are a useful tool for students selecting their PhD or postdoc topics and environments. A must for anyone in academia and research working in this important field.Content: Chapter 1 Catalytic Enantioselective Alkylation of Prochiral Ketone Enolates (pages 1–10): Corey M. Reeves and Brian M. StoltzChapter 2 Point?to?Planar Chirality Transfer in Total Synthesis: Scalable and Programmable Synthesis of Haouamine A and Its Atropisomer (pages 11–16): Noah Z. Burns and Phil S. BaranChapter 3 Tethered Aminohydroxylation (pages 17–27): Timothy J. Donohoe and Stefanie MeschChapter 4 Organocatalyzed Transformations of a, a?Unsaturated Carbonyl Compounds through Iminium Ion Intermediates (pages 29–34): Julian H. Rowley and Nicholas C. O. TomkinsonChapter 5 The Renaissance of Silicon?Stereogenic Silanes: A Personal Account (pages 35–42): Andreas Weickgenannt and Martin OestreichChapter 6 Asymmetric Dienamine Activation (pages 43–48): Mathias ChristmannChapter 7 Asymmetric Bronsted Acid Catalysis (pages 49–53): Iuliana Atodiresei, Uxue Uria and Magnus RuepingChapter 8 Quaternary Stereogenic Centers by Enantioselective a?Carbon Eliminations from tert?Cyclobutanols (pages 55–59): Nicolai Cramer and Tobias SeiserChapter 9 Total Synthesis of Oseltamivir and ABT?341 Using One?Pot Technology (pages 61–66): Hayato Ishikawa and Yujiro HayashiChapter 10 Enantioselective Annulations with Chiral N?Mesityl N?Heterocyclic Carbenes (pages 67–77): Jessada Mahatthananchai and Jeffrey W. BodeChapter 11 Asymmetric Counteranion?Directed Catalysis (ACDC) (pages 79–85): Manuel Mahlau and Benjamin ListChapter 12 Enantioselective Organo?SOMO Catalysis: a Novel Activation Mode for Asymmetric Synthesis (pages 87–94): David W. C. Macmillan and Sebastian RendlerChapter 13 Enantioselective Passerini Reaction (pages 95–101): Qian Wang, Jieping Zhu and Mei?Xiang WangChapter 14 Rapid Enantiomeric Excess Determination (pages 103–107): Oliver TrappChapter 15 Asymmetric Catalysis of Reversible Reactions (pages 109–115): Lukas HintermannChapter 16 Exploiting Fluorine Conformational Effects in Organocatalyst Design: The Fluorine–Iminium Ion Gauche Effect (pages 117–124): Christof Sparr, Lucie E. Zimmer and Ryan GilmourChapter 17 Dutch Resolution (pages 125–130): Richard M. KelloggChapter 18 Construction of anti?Me?OH Vicinal Relationships in Polyketides (pages 131–137): Vaidotas Navickas and Martin E. MaierChapter 19 Photoswitchable General Base Catalysts (pages 139–145): Philipp Viehmann and Stefan HechtChapter 20 Asymmetric Halonium Addition to Olefins (pages 147–155): Scott A. Snyder and Alexandria P. BrucksChapter 21 Catalytic Asymmetric Gosteli–Claisen Rearrangement (CAGC) (pages 157–163): Julia Rehbein and Martin HiersemannChapter 22 Biomimetic Total Synthesis of the Penifulvin Family (pages 165–177): Tanja Gaich and Johann MulzerChapter 23 Catalyst?Controlled 1,3?Polyol Syntheses (pages 179–186): Tobias Harschneck and Stefan F. KirschChapter 24 Enantioselective Carbonyl Allylation and Crotylation from the Alcohol Oxidation Level via C–C Bond Forming Transfer Hydrogenation (pages 187–196): Joseph Moran and Michael J. KrischeChapter 25 Stereoselective Synthesis with Hypervalent Iodine Reagents (pages 197–203): Umar Farid and Thomas WirthChapter 26 Asymmetric Gold?Catalyzed Reactions (pages 205–211): Neuria Huguet and Antonio M. EchavarrenChapter 27 Asymmetric Catalysis in the Total Synthesis of Lipids and Polyketides (pages 213–219): Santiago Barroso and Adriaan J. MinnaardChapter 28 The Evolving Role of Biocatalysis in Asymmetric Synthesis (pages 221–231): Meelanie Hall, Wolfgang Kroutil and Kurt FaberChapter 29 Bifunctional Thiourea Catalysts (pages 233–237): Yoshiji Takemoto and Tsubasa InokumaChapter 30 Catalytic Asymmetric (4 + 3) Cycloadditions Using Allenamides (pages 239–248): Yun?Fei Du and Richard P. HsungChapter 31 Application of the Achmatowicz Rearrangement for the Synthesis of Oligosaccharides (pages 249–259): Michael F. Cuccarese and George A. O'dohertyChapter 32 Asymmetric C–C Bond Formation Using Chiral Phosphoric Acid (pages 261–266): Takahiko AkiyamaChapter 33 Asymmetric C–H Bond Functionalization (pages 267–272): Masayuki Wasa, Kelvin S. L. Chan and Jin?Quan YuChapter 34 Asymmetric C–C Bond Formation Using Chiral Guanidine Catalysts (pages 273–278): Masahiro TeradaChapter 35 Enantioselective Synthesis of Lactones via Rh?Catalyzed Ketone Hydroacylation (pages 279–284): Matthew M. Coulter and Vy M. DongChapter 36 Radical Haloalkylation (pages 285–291): Armen ZakarianChapter 37 Asymmetric Hydrovinylation of Alkenes (pages 293–301): T. V. (babu) RajanbabuChapter 38 Heterocycle Construction via Asymmetric Rhodium?Catalyzed Cycloadditions (pages 303–308): Kevin M. Oberg and Tomislav RovisChapter 39 N?Heterocyclic Carbene?Catalyzed Aldol Desymmetrizations (pages 309–316): Karl A. Scheidt, Eric M. Phillips and Julien Dugal?TessierChapter 40 Strategies for the Asymmetric Total Synthesis of Natural Products: ‘‘Chiral Pool’’ versus Chiral Catalysts (pages 317–322): Karl GademannChapter 41 Dynamic Kinetic Asymmetric Transformations Involving Carbon–Carbon Bond Cleavage (pages 323–332): Andrew T. Parsons and Jeffrey S. JohnsonChapter 42 Iron?Catalyzed Allylic Substitutions (pages 333–341): Markus Jegelka and Bernd PlietkerChapter 43 Asymmetric Conia?ene Carbocyclizations (pages 343–351): Filippo Sladojevich and Darren J. DixonChapter 44 Tactics and Strategies in the Total Synthesis of Chlorosulfolipids (pages 353–361): Christian Nilewski and Erick M. CarreiraChapter 45 Linear Free Energy Relationships (LFERs) in Asymmetric Catalysis (pages 363–370): Elizabeth N. Bess and Matthew S. SigmanChapter 46 Asymmetric Diamination of Alkenes (pages 371–375): Josee A. Souto and Kilian Mu?nizChapter 47 Enzymatic Asymmetric Synthesis of Tertiary Alcohols (pages 377–381): Michael RichterChapter 48 Oxidative Dearomatization and Organocatalytic Desymmetrization (pages 383–390): Alice E. Williamson and Matthew J. GauntChapter 49 Total Synthesis of All (–)?Agelastatin Alkaloids (pages 391–396): Mohammad Movassaghi and Sunkyu Han