ENGLISH

Prostaglandins, Leukotrienes, and the Immune Response

By John L. Ninnemann

Book information

Year
2006
ISBN
9780521031714, 9780511600364, 0521334837, 0521031710, 0511600364, 9780521334839
LCC
QP801.P68 N55 1988
Open Library ID
OL2404751M
Language
english
Format
PDF
Filesize
6 MB (6693998 bytes)
Pages
236\232
Time added
2011-06-04 13:46:07

Description

This study looks at the way the products of arachidonic acid metabolism are active both in normal and abnormal immune responses. While some of the fundamental issues such as whether lymphocytes are capable of producing prostaglandins and leukotrienes are still hotly debated, the evidence is overwhelming that many specific immunological problems and disease states are associated with alterations in the normal balance of arachidonic acid metabolism. This book provides a review of the history and chemistry of the arachidonic acid cascade as well as an exhaustive survey of the literature concerning the interaction of arachidonic acid metabolites with cells of the immune system. The author also presents and discusses the evidence demonstrating prostaglandin and leukotriene participation in response to injury and in malignancy, tissue and organ rejection, rheumatoid arthritis, autoimmunity and allergy.

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