ENGLISH

The Adenosinergic System: A Non-Dopaminergic Target in Parkinson’s Disease

By Micaela Morelli , Nicola Simola , Jadwiga Wardas (eds.)

Book information

Publisher
Springer International Publishing
Year
2015
ISBN
978-3-319-20272-3, 978-3-319-20273-0
DOI
10.1007/978-3-319-20273-0
Language
english
Format
PDF
Filesize
9 MB (9198324 bytes)
Series
Current Topics in Neurotoxicity 10
Edition
1
Pages
XII, 337\344
Time added
2015-11-25 16:51:03
Neurosciences; Neurology

Description

Adenosine A2A receptor antagonists have shown great promise in the treatment of Parkinson's Disease and alleviation of symptoms. This book addresses various aspects of this class of drugs from their chemical development to their clinical use. Among the many insightful chapters contained in this book, there are three unique reviews that have not previously been published in any format: (1) a history of istradefylline, the first A2A antagonist approved for treatment of Parkinson's Disease, (2) an overview of neuroimaging studies in human death and disease and (3) a study of urate as a possible biomarker and neuroprotectant.

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