Oncology in the Precision Medicine Era: Value-Based Medicine

Description

This volume comprehensively reviews oncology in the precision medicine era of personalized care, latest developments in the field, and indications and clinical trials for the treatment of cancer with targeted therapies, immunotherapy, and epigenetic modulators. It thoroughly addresses concerns of various types of cancers including cancers of the head and neck, lung, colon, esophagus, bladder, pancreas, and breast; melanoma; multiple myeloma; hepatocellular carcinoma; renal cell carcinoma; and sarcomas. It is organized and written in a format that is easy to follow for both clinicians and non-clinical scientists interested in personalized medicine. Chapters cover the identification of the clinical problem and summary of recent findings, tumor biology and heterogeneity, genomics, examples of simple and complex cases, biological pathways, future clinical trials, and financial considerations. Oncology in the Precision Medicine Era: Value-Based Medicine will serve as a useful resource for medical oncologists and healthcare providers tailoring medicine to the needs of the individual patient, from prevention and diagnosis to treatment and follow up. Front Matter ....Pages i-xiii Healthcare Perspective (Joseph C. Alvarnas)....Pages 1-12 Lung Cancer (Joy Huang, Ashley Abing, Karen L. Reckamp)....Pages 13-30 Esophageal and Gastric Cancer (Michael J. Jang, Joseph Chao)....Pages 31-46 Sarcomas (An Ngoc Nhu Uche, Warren A. Chow)....Pages 47-59 Multiple Myeloma (Amrita Krishnan, Nitya Nathwani, Idoroenyi Amanam, Rohan Gupta)....Pages 61-95 Pancreatic Cancer (Addie Hill, Vincent Chung)....Pages 97-109 Colon Cancer (Blase Polite)....Pages 111-121 Renal Cell Carcinoma (Yash Dara, Nicholas Salgia, Sumanta K. Pal)....Pages 123-133 Prostate Cancer (Bertram Yuh, Zijie Sun)....Pages 135-149 Bladder Cancer (Tanya Dorff, Petros Grivas)....Pages 151-169 Molecular Testing in Ovarian Cancer: Recommendations and Treatment Considerations (Kathy Pan, Mihaela C. Cristea)....Pages 171-186 Genomic Cancer Risk Assessment (Jeffrey N. Weitzel, Thomas P. Slavin)....Pages 187-207 Triple-Negative Breast Cancer (Ritika Vankina, Yuan Yuan)....Pages 209-223 Melanoma (Kathryn Bollin, Kim Margolin)....Pages 225-246 Digital Patient Engagement and Social Media (Virginia Sun)....Pages 247-258 Hepatocellular Carcinoma (Rebecca Allen, Daneng Li)....Pages 259-271 Treatment Strategies in Head and Neck Cancers (Dan Zhao, Rebecca Pharaon, Erminia Massarelli)....Pages 273-294 Primary Central Nervous System Tumors (Rimas V. Lukas, Vinai Gondi, Orin Bloch, Maciej M. Mrugala)....Pages 295-325 Lymphoma (Leslie Popplewell)....Pages 327-340 Back Matter ....Pages 341-351