ENGLISH

Replicating Vaccines: A New Generation (Birkhauser Advances in Infectious Diseases)

By Rino Rappuoli , Philip R. Dormitzer , Christian W. Mandl

Book information

Year
2010
ISBN
3034602766, 9783034602761, 3034602774, 9783034602778
Language
english
Format
PDF
Filesize
5 MB (4897343 bytes)
Edition
1st Edition.
Pages
461\461
Time added
2011-06-04 13:46:07

Description

Technological advances, together with a better understanding of the molecular biology of infectious microorganisms, are creating exciting possibilities for a new generation of replicating vaccines. Historically, live vaccines have been either directly derived from a natural source or attenuated by empirical approaches using serial passages and host cell adaptation. Currently, we are witnessing a quantum leap in our technological capabilities to specifically modify the genetic make-up of viruses and bacteria, making it possible to generate improved live vaccines and to develop completely new types of replicating vaccines, such as vectored vaccines, single-round infectious vaccines and replicon vaccines. This book highlights some of the most exciting recent developments towards a new generation of replicating vaccines.

Similar books