ENGLISH

Chimerism

By Nicole L. Draper

Book information

Publisher
Springer International Publishing
Year
2018
ISBN
978-3-319-89865-0, 978-3-319-89866-7
Language
english
Format
PDF
Filesize
3 MB (3095198 bytes)
Edition
1st ed.
Pages
XI, 200\201
Time added
2018-08-15 07:07:45
Medicine & Public Health; Hematology; Blood Transf

Description

This text provides a comprehensive, up-to-date review of chimerism. The first part of the volume presents the causes of chimerism, specifically focusing on fertilization and early embryonic errors, pregnancy and multiple gestations, and transplantation and transfusion. The second part of the volume outlines clinical identification and consequences of chimerism. Chapters in this section focus on the effects of chimerism on testing in relationship determination and forensics, prenatal genetic testing and screening, and blood and HLA typing. This part also reviews new data concerning matching donors and recipients for transplantation, while outlining the risks of transplantation, such as graft-vs-host disease and passenger lymphocyte syndrome. Additionally, evidence on the role of chimerism in autoimmune disease and cancer is presented. Written by experts in the field, Chimerism: A Clinical Guide is a valuable resource for clinicians and researchers that will help guide patient management and stimulate investigative efforts. Front Matter ....Pages i-xi Front Matter ....Pages 1-1 Fertilization and Early Embryonic Errors (Nicole L. Draper, Kristy Crooks)....Pages 3-17 Pregnancy and Multiple Gestations (Linda Marie Randolph, Ramen H. Chmait)....Pages 19-31 Transplantation and Transfusion (Joel N. Kniep)....Pages 33-48 Front Matter ....Pages 49-49 Relationship Testing and Forensics (Kayla Sheets, Robert Wenk)....Pages 51-63 Prenatal Genetic Testing and Screening (Ignatia B. Van den Veyver)....Pages 65-79 Blood Typing Discrepancies (Opal L. Reddy, Dawn C. Ward, Andrea M. McGonigle)....Pages 81-103 Hematopoietic Stem Cell Donor Selection and Graft-Versus-Host Disease (Alexa J. Siddon, Christopher A. Tormey)....Pages 105-117 Passenger Lymphocyte Syndrome (Nicole L. Draper, Jamie E. Kallan)....Pages 119-134 Chimerism: A Clinical Guide to Tolerance Induction (Andrea R. Merchak, Anita Y. Chhabra, Joseph R. Leventhal, Suzanne T. Ildstad)....Pages 135-152 Autoimmune Disease (Nathalie Lambert)....Pages 153-179 Cancer (Valentina Cirello, Laura Fugazzola)....Pages 181-194 Back Matter ....Pages 195-200

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