ENGLISH

Integrated Genomics: A Discovery-Based Laboratory Course

By Guy A. Caldwell (Author) , Shelli N. Williams (Author) , Kim A. Caldwell (Author)

Book information

Publisher
Wiley
Year
2006
ISBN
0470095016, 9780470095010, 9780470095034
Open Library ID
OL7595941M
Language
english
Format
PDF
Filesize
11 MB (11356895 bytes)
Edition
1
Pages
246\246
Time added
2011-08-31 04:54:40

Description

Integrated Genomics: A Discovery-Based Laboratory Course introduces the excitement of discovery to the basic molecular biology laboratory. Utilizing up-to-date molecular biology protocols and a basic experimental design, this text offers experience with three different model systems. Students will become familiar with the simplicity and power of single-celled organisms, Escherichia coli and Saccharomyces cerevisiae, as they search for genes that interact and function within the nematode Caenorhabditis elegans.Incorporated throughout the course are exercises designed to offer students familiarity with the wealth of bioinformatics data that can be accessed on the World Wide Web. Following completion of interaction studies within the yeast, the course is designed to allow students to examine the functional consequences of reducing a gene’s function within the multicellular worm that is both simple and inexpensive to maintain within a laboratory. The inclusion of alternative experiments allow for flexibility in determining the ending date or goal of the laboratory, as well as working within the available budget and resources of most any classroom environment.Further striking features of this title are:An accompanying Web site providing PowerPoint slides, plus links to the internet, and regular updates as bioinformatics databases evolve and methods improve. www.wiley.com/go/caldwellInclusion of modern genomic/proteomic technologies such as the yeast two-hybrid system and RNAiDetailed experimental protocols and easy access to instructional materialsThis discovery-based laboratory course provides excellent practical training for those pursuing career paths in biomedicine, pharmacy, and biotechnology.

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