ENGLISH

Vertebrate Photoreceptors: Functional Molecular Bases

By Takahisa Furukawa , James B. Hurley , Satoru Kawamura (eds.)

Book information

Publisher
Springer Japan
Year
2014
ISBN
978-4-431-54879-9, 978-4-431-54880-5
DOI
10.1007/978-4-431-54880-5
Language
english
Format
PDF
Filesize
7 MB (7082629 bytes)
Edition
1
Pages
349\350
Time added
2014-06-12 06:00:00
Neurosciences; Cell Biology; Evolutionary Biology;

Description

This book provides a series of comprehensive views on various important aspects of vertebrate photoreceptors. The vertebrate retina is a tissue that provides unique experimental advantages to neuroscientists. Photoreceptor neurons are abundant in this tissue and they are readily identifiable and easily isolated. These features make them an outstanding model for studying neuronal mechanisms of signal transduction, adaptation, synaptic transmission, development, differentiation, diseases and regeneration. Thanks to recent advances in genetic analysis, it also is possible to link biochemical and physiological investigations to understand the molecular mechanisms of vertebrate photoreceptors within a functioning retina in a living animal. Photoreceptors are the most deeply studied sensory receptor cells, but readers will find that many important questions remain. We still do not know how photoreceptors, visual pigments and their signaling pathways evolved, how they were generated and how they are maintained. This book will make clear what is known and what is not known. The chapters are selected from fields of studies that have contributed to a broad understanding of the birth, development, structure, function and death of photoreceptor neurons. The underlying common word in all of the chapters that is used to describe these mechanisms is “molecule”. Only with this word can we understand how these highly specific neurons function and survive. It is challenging for even the foremost researchers to cover all aspects of the subject. Understanding photoreceptors from several different points of view that share a molecular perspective will provide readers with a useful interdisciplinary perspective.

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