New Developments in Nanosensors for Pharmaceutical Analysis

Description

New Developments for Nanosensors in Pharmaceutical Analysis presents an overview of developments in nanosensor usage in pharmaceutical analysis, thereby helping pharmaceutical companies attain reliable, precise, and accurate analysis of pharmaceuticals. This book presents very simple, precise, sensitive, selective, fast, and relatively inexpensive methods for pre-treatment, prior to analysis. These methods may be considered for further application in clinical studies and assays. The book includes the manufacturing of sensors for pharmaceutical analysis at nano- or smaller scales, and gives simple and relatable designs for the fabrication of sensors. Twelve chapters cover an introduction to the topic, immobilization techniques, mechanism effect of nanomaterials on structure, optical nanosensors for pharmaceutical detection, chemical nanosensors in pharmaceutical analysis, noble metal nanoparticles in electrochemical analysis of drugs, photo-electrochemical nanosensors for drug analysis, molecularly imprinted polymer based nanosensors for pharmaceutical analysis, nanomaterials for drug delivery systems, nanomaterials enriched nucleic acid-based biosensors, nanosensors in biomarker detection, and nanomaterials-based enzyme biosensors for electrochemical applications. Cover NEW DEVELOPMENTS IN NANOSENSORS FOR PHARMACEUTICAL ANALYSIS Copyright Contributors About the Authors Preface 1 Introduction to Nanosensors Introduction Nanoparticles in Nanosensors and Their Broad Applications Metal-Based Nanoparticles and Their Broad Applications Metal-Based NPs as Gas Sensors Metal-Based NPs as OLEDs Magnetic Metal-Based NPs Metal-Based NPs as Sunscreens Metal-Based NPs in Virology and Bacteriology Metal-Based NPs as Supercapacitors Carbon-Based Nanomaterials Carbon-Based Nanomaterials as Gas Sensors Carbon-Based Nanomaterials as Electrochemical Sensors and in Fluorescence Quenching Carbon Nanomaterials as High-Performance Energy Storage Devices Molecularly Imprinted Polymer-Based Nanosensors MIP-Functionalized SPE MIPs Functionalized as Magnetic MIPs MIPs Modified With Carbon Nanomaterials MIPs as Sensors Dendrimers Dendrimer-Nanostructured Hybrid System Dendrimers Conjugated to Carbon-Based Nanomaterials Conclusions References Further Reading 2 Immobilization Techniques of Nanomaterials Introduction Nanomaterials Used in Biosensors for Pharmaceutical Detection Carbon Nanomaterials Carbon Nanotubes Graphene Fullerene Quantum Dots Metal Nanoparticles Magnetic Nanoparticles Modification Strategies for Nanomaterial-Based Biosensors Drop Casting Electrochemical Deposition Electrochemical Polymerization Molecularly Imprinted Polymer Self-Assembly and Adsorption of Nanomaterials Addition Nanomaterials in Carbon Paste Electrodes Conclusion References 3 The Effect of Nanomaterials on the Drug Analysis Performance of Nanosensors Introduction Nanomaterials Used for Sensor Development Morphological and Structural Characterization Techniques for Nanomaterials Techniques Used for the Characterization of the Sensor Effect of Electrodes Fabricated From Nanomaterials Role of the Structure of Nanomaterials in Enhancing the Sensitivity and Selectivity of Sensors The Shape Effect of Nanostructures on Drug Analyzer Nanosensors Morphological Effect of Specific Nanomaterials-Based Sensors Types of Nanostructures Carbon Nanostructure-Based Sensors Polymeric Nanostructures as Nanosensors Transition Metal Nanostructures for Nanosensors Sensors Fabricated From Nanocomposites, Nanohybrids, and Nanobimetallic Alloys The Effect of Crystal Phases and Structural Units on Nanosensors Selective and Simultaneous Detection of Drugs by a Specific Nanosensor in Analyte Samples Conclusion and Future Perspectives References Further Reading 4 Optical Nanosensors for Pharmaceutical Detection Introduction Chemical and Bio-Based Optical Nanosensors Surface-Enhanced Raman Spectroscopy Localized Surface Plasmon Resonance-Based Optical Nanosensors Fluorescence-Based Optical Biosensors Chemical Modification of Nanosensors Conclusion References 5 Chemical Nanosensors in Pharmaceutical Analysis Introduction to Chemical Nanosensors Transducer Types in Chemical Nanosensors Nanomaterials in Chemical Nanosensors Carbon-Based Nanomaterials in Chemical Nanosensors Metal-Based Nanomaterials in Chemical Nanosensors Polymer-Based Chemical Nanosensors Conclusion References Further Reading 6 Noble Metal Nanoparticles in Electrochemical Analysis of Drugs Introduction Noble Metals Ruthenium Rhodium Palladium Iridium Platinum Gold Silver Electrochemical Techniques The Functions of Noble Metal Nanoparticles Applications of Noble Metal Nanoparticles for Electrochemical Drug Analysis Conclusion References Further Reading 7 Photoelectrochemical Nanosensors Introduction The Effect of the Morphology of Nanomaterials on the Detection Ability of Photoelectrochemical Sensors Quantum Dots in Photoelectrochemical Sensors Molecularly Imprinted Polymers in Photoelectrochemical Sensors Photoelectrochemical Nanobiosensors: Fabrication Techniques and the Measurements Recent Developments in Photoelectrochemical Nanosensors for the Determination of Pharmaceuticals, Chemicals, Cancer Bio ... Conclusion References Further Reading 8 Molecularly Imprinted Polymer-Based Nanosensors for Pharmaceutical Analysis Introduction Molecularly Imprinted Polymers Nanomaterials in molecularly imprinted polymers Carbon Nanomaterials Metal-based nanoparticles Sensor Configurations Conclusion References Further Reading 9 Nanomaterials for Drug Delivery Systems Introduction Drug Delivery Systems Why Nanomaterials? Types of Nanomaterials Dendrimers Liposomes Solid Lipid Nanocarriers Micelles Polymeric Nanoparticles Inorganic Nanoparticles Metal Nanoparticles Ceramic Nanoparticles Silica Nanoparticles Carbon-Based Nanomaterials Fullerenes Graphene Carbon Nanotubes Diamonds Conclusion References 10 Nanomaterials-Enriched Nucleic Acid-Based Biosensors Introduction Electrochemical Biosensors Voltammetric Nucleic Acid Biosensors Impedimetric-Based Nucleic Acid Biosensors Amperometric-Based Nucleic Acid Biosensors QCM Biosensors Optical Nucleic Acid Biosensors Colorimetric Nucleic Acid Biosensors Fluorescence-Based Nucleic Acid Biosensors Chemiluminescence-Based Nucleic Acid Biosensors Electrochemiluminescence-Based Nucleic Acid Biosensors Surface-enhanced Raman Spectroscopy (SERS)-Based Nucleic Acid Biosensors SPR-Based Nucleic Acid Biosensors Conclusion Acknowledgments References 11 Nanosensors in Biomarker Detection Introduction Biomarkers Nanomaterials for Sensor Design Carbon Nanotubes Graphene Metal Nanoparticles Methods for Biomarker Detection and Determination Electrochemical Methods Optical Methods Conclusion and Future Prospects References 12 Nanomaterials-Based Enzyme Biosensors for Electrochemical Applications: Recent Trends and Future Prospects Introduction Electrochemical Enzyme Biosensors Nanomaterials-Based Electrochemical Enzyme Biosensors Carbon Nanotubes-Based Electrochemical Enzyme Biosensors Graphene-Based Electrochemical Enzyme Biosensors Nanoparticles-Based Electrochemical Enzyme Biosensors Nanostructured Polymers-Based Electrochemical Enzyme Biosensors Electrochemical Biosensors Based on Combinations of Different Nanomaterials Conclusions and Prospects Acknowledgments References Index A B C D E F G H I L M N O P Q R S T V W X Z Back Cover