Scale-Up Processes: Iterative Methods for the Chemical, Mineral and Biological Industries

Description

Common scale-up methods are conventional where the blind　piloting is essential.　This imposes huge investment and leads to failures mostly in solid processing.　However, the limitations of resources, current shortcomings, short time-to-market demand are forced companies to minimize piloting. With these situations in mind, current digitalization outlook and computational facilities, we proposed and developed a novel iterative scale up method with case studies which highly expedites the process innovation through the following key sequences: To move from literature and laboratory studies to commercial design. To reduce risks by reevaluating literature, lab studies, e-pilot or adequate pilots if needed. To iterate between commercial to lab, e-pilot and pilot with CAPEX, OPEX and LCA. Preface About the Editors Contents 1 Conventional scale-up method: challenges and opportunities 2 Iterative scale-up method: concept and basics 3 Process extrapolation by simulation 4 Transition from e-pilot to full commercial scale 5 Life-cycle assessment and technology scale-up 6 Case study I: n-Butane partial oxidation to maleic anhydride: VPP manufacture 7 Case study II: n-Butane partial oxidation to maleic anhydride: commercial design 8 Case study III: Methanol to olefins 9 Case study IV: Hydropotash from potassium feldspar 10 Case study V: Lactide production process development 11 Case study VI: CO2 sequestration in microalgae photobioreactors 12 Discussion and concluding remarks Index