ENGLISH

Toll-Like Receptors: Methods and Protocols

By Jakub Siednienko , Sinead M. Miggin (auth.) , Claire E. McCoy , Luke A. J. O’Neill (eds.)

Book information

Publisher
Humana Press
Year
2009
ISBN
9781934115725, 193411572X
DOI
10.1007/978-1-59745-541-1
Language
english
Format
PDF
Filesize
4 MB (4636491 bytes)
Series
Methods in Molecular Biology 517
Edition
1
Pages
376\438
Topic
Biology
Library
kolxoz-dop
Time added
2010-02-18 13:16:04
Immunology; Cytokines and Growth Factors

Description

In addition to their invaluable role in the fight against infection, Toll-Like Receptors (TLRs) in an under- or over-active state can lead to the pathogenesis of disease, making these receptors a key focal point for many research laboratories. In Toll-Like Receptors: Methods and Protocols, experts in the field contribute techniques currently used to study TLRs, their downstream signalling pathways, and their role in the pathogenesis of disease, with sections examining TLR expression and the application of genetic techniques and microarray analysis to TLR research. Written in the highly successful Methods in Molecular Biology™ series format, chapters include brief introductions to the topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and Notes sections highlighting tips on troubleshooting and avoiding known pitfalls. Versatile and cutting-edge, Toll-Like Receptors: Methods and Protocols provides an ideal manual for a wide range of biologists and medical researchers studying these vital components of the immune system.

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