Improving Outcomes in Oral Cancer: A Clinical and Translational Update

Description

This book brings together experts in the field of maxillofacial and head and neck oncology to provide a comprehensive clinical and translational update on oral cancer that focuses especially on prognosis. Readers will find up-to-date information on disease staging and the pathological, genetic, and surgical factors that affect patient outcomes. Individual chapters describe the most recent advances in radiotherapy, chemotherapy, and immunotherapy, again with careful analysis of the treatment-related factors relevant to response and survival. Management of premalignant lesions and risk factors for malignant transformation are discussed, and the latest knowledge on chemoprevention is presented. Further topics to be addressed include reconstruction of oral cancer defects, salvage options in the event of recurrence, and the prediction of quality of life following treatment. The book will be of value to all clinicians who care for patients with oral cancer in their everyday practice. Front Matter ....Pages i-vii Oral Epithelial Dysplasia (Kenneth Wan, Deepak Kademani)....Pages 1-12 Chemoprevention in Oral Cancer (Jeffrey Y. Tsai, Jasjit K. Dillon)....Pages 13-22 Diagnostic Adjuncts for Screening and Surveillance in Head and Neck Cancer (James Murphy, Mohammed Qaisi)....Pages 23-32 Current Updates in Staging and Prognosis in Oral Cancer (Paul Covello, D. David Kim)....Pages 33-43 Surgical Factors Affecting Outcomes in Oral Squamous Cell Carcinoma (Justine Moe, Andrew Baker, Brent Ward)....Pages 45-63 Pathological Factors Affecting Outcomes in Oral Cancer (Eric R. Carlson, J. Michael McCoy)....Pages 65-95 Genetics of Oral Cancer (Anthony Morlandt, Hope Amm)....Pages 97-103 Factors Affecting Response and Survival in Radiotherapy (Michael Awadallah, Kurt Nisi, Ketan J. Patel)....Pages 105-115 Novel and Emerging Chemotherapeutic Agents in Head and Neck Cancer (Arielle Elkrief, Nicholas Makhoul, Nathaniel Bouganim)....Pages 117-128 Immunotherapy in Oral Cancer: A Fourth Dimension of Cancer Treatment (Marcus A. Couey, Rom S. Leidner, Simon W. Young, R. Bryan Bell)....Pages 129-154 Recurrent Oral Cancer and Salvage Options (Joshua E. Lubek, Michael Nagai)....Pages 155-164 Oral Reconstruction (J. Collin, B. Turner, R. Fernandes)....Pages 165-179 Predicting Quality of Life (QoL) of Oral Cancer (Roderick Y. Kim, Jason N. Burkes, Fayette C. Williams)....Pages 181-189