Nervous System

Description

The International Life Sciences Institute (ILSI) was estab­ lished in 1978 to stimulate and support scientific research and educational programs related to nutrition, toxicology, and food safety, and to encourage cooperation in these programs among scientists in universities, industry, and government agencies to assist in the resolution of health and safety issues. To supplement and enhance these efforts, ILSI has made a major commitment to supporting programs to harmon­ ize toxicological testing, to advance a more uniform inter­ pretation of bioassay results worldwide, to promote a common understanding of lesion classifications, and to encourage wide discussion of these topics among scien­ tists. The Monographs on the Pathology of Laboratory Ani­ mals are designed to facilitate communication among those involved in the safety testing of foods, drugs, and chemicals. The complete set will cover all organ systems and is intended for use by pathologists, toxicologists, and others concerned with evaluating toxicity and carcinogen­ icity studies. The international nature of the project - as reflected in the composition of the editorial board and the diversity of the authors and editors - strengthens our ex­ pectations that understanding and cooperation will be im­ proved worldwide through the series. Alex Malaspina President International Life Sciences Institute Preface This book, on the nervous system, is the sixth volume of a set pre­ pared under the sponsorship of the International Life Sciences Insti­ tute (ILSI). Front Matter....Pages I-XVI Microvasculature in Experimental Glioma and Developing Brain, Rat....Pages 1-6 Experimental Allergic Encephalomyelitis, Rat....Pages 6-16 Neurotoxic Effects of Pyridoxine (Megavitaminosis B6), Rat....Pages 17-24 Neurotoxic Effects of Doxorubicin, Rat....Pages 25-28 Neurotoxic Effects of Clinoquinol, Mouse....Pages 29-32 Neurotoxic Effects of Hexacarbons ( n -Hexane, Methyl- n -Butylketones; 2,5-Hexane-Dione; 1,4-Diketones)....Pages 32-41 Organophosphorus Ester-Induced Delayed Neuropathy, Rat....Pages 41-47 Neurotoxic Effects of Ethidium Bromide, Rat....Pages 47-52 Neurotoxic Effects of 6-Aminonicotinamide, Mouse....Pages 53-57 Neurotoxic Effects of Trimethyltin....Pages 58-63 Neurotoxic Effects of Lysolecithin, Mouse, Rat....Pages 63-73 Neurotoxicity of Perhexiline Maleate in Rats....Pages 74-77 Cycloleucine Encephalopathy, Rats and Mice....Pages 77-83 Neurotoxic Effects of Amoscanate, Rat....Pages 84-87 Neurotoxic Effects of 2-Chloroprocaine and Other Local Anesthetics, Rat....Pages 87-92 Systemic Degenerative Disorders of Primary Sensory Neurons in Rats Induced by 4-Hydroxyaminoquinoline 1-Oxide....Pages 92-98 Inorganic Mercury Poisoning, Rat....Pages 98-101 Tellurium Poisoning, Rat....Pages 101-103 Cadmium Poisoning, Rat....Pages 104-107 Benign and Malignant Neoplasms, Meninges, Rat....Pages 108-117 Malignant Reticulosis, Rat....Pages 117-123 Gliomas, Mouse....Pages 123-130 Lipoma, Brain, Mouse....Pages 130-134 Gliomas, Rat....Pages 134-143 Peripheral Nerve Sheath Tumors, Rat....Pages 143-154 Schwannomas (Induced), Cranial, Spinal, and Peripheral Nerves, Rat....Pages 154-160 Malignant Melanotic Schwannomas Induced by 1,1-Dimethylhydrazine, European Hamster....Pages 160-164 Cardiac Neurilemmoma, Rat....Pages 165-169 Parvovirus Infection, Rat....Pages 170-175 Encephalomyelitis, Theiler’s Virus, Mouse....Pages 175-179 Mouse Hepatitis Virus Infection, Brain, Mouse....Pages 180-186 Lymphocytic Choriomeningitis, Mouse....Pages 187-191 Encephalitozoonosis, Central Nervous System, Rat, Mouse....Pages 192-197 Toxoplasmosis, Nervous System, Mouse and Hamster....Pages 197-202 Spontaneous Radiculoneuropathy, Aged Rats....Pages 203-208 Peripheral Neuropathy in the Mutant Syrian Hamster....Pages 208-215 Aberrant Synaptic Development in Mutant “Weaver” Mice....Pages 215-221 Back Matter....Pages 222-233