Cigarette Smoke Toxicity: Linking Individual Chemicals to Human Diseases

Description

Smoking causes and contributes to a large number of human diseases, yet due to the large number of potentially hazardous compounds in cigarette smoke -- almost 5,000 chemicals have been identified, establishing the link between smoking and disease has often proved difficult. This unbiased and scientifically accurate overview of current knowledge begins with an overview of the chemical constituents in cigarette smoke, their fate in the human body, and their documented toxic effects on various cells and tissues. Recent results detailing the many ways components of cigarette smoke adversely affect human health are also presented, highlighting the role of smoking in cardiovascular, respiratory, infectious and other diseases. A final chapter discusses current strategies for the treatment and prevention of smoking-induced illness. Despite the obvious importance of the topic, this is the first comprehensive reference on tobacco smoke toxicity, making for essential reading for all toxicologists and healthcare professionals dealing with smoking-related diseases.Content: Chapter 1 From Discarded Leaf to Global Scourge – The Extraordinary History of the Ascent of Tobacco and its Many Modes of Consumption (pages 1–15): Barry A. Finegan and Garrett J. FineganChapter 2 Components of a Cigarette (pages 17–35): Andreas ZemannChapter 3 The Process of Cigarette Smoking (pages 37–53): Jian Wang and Xing Li WangChapter 4 Smoke Chemistry (pages 55–66): Andreas ZemannChapter 5 Exposure to Tobacco Smoke (pages 67–91): Andre ConradChapter 6 An Epidemiological Appraisal of Smoking?Related Outcomes (pages 93–120): Elke Munters and Tim S. NawrotChapter 7 Smoking and Cardiovascular Diseases (pages 121–144): PD Dr. David BernhardChapter 8 Smoking and Cancer (pages 145–166): Parimal Chowdhury and Stewart MacLeodChapter 9 Smoking and COPD and Other Respiratory Diseases (pages 167–190): Thomas E. Sussan and Shyam BiswalChapter 10 Smoking, Infectious Diseases and Innate Immune (Dys)function (pages 191–215): David A. Scott and Juhi BagaitkarChapter 11 Smoking and Reproduction (pages 217–237): Martina PrelogChapter 12 Smoking Tobacco and Gastrointestinal Pathophysiology and Diseases (pages 239–256): Hitoshi AsakuraChapter 13 Smoking and Oral Health (pages 257–280): Eman Allam, Weiping Zhang, Cunge Zheng, Richard L. Gregory and L. Jack WindsorChapter 14 Smoking and Eye Diseases (pages 281–309): Maria E. Marin?Castano and Marianne PonsChapter 15 Smoking: Prevention and Cessation (pages 311–328): Adam CsordasChapter 16 Interfering with Smoking?Induced Pathophysiology (pages 329–353): Adam CsordasChapter 17 Summary (pages 355–359): PD Dr. David Bernhard