ENGLISH

Mycobacteria and Tb (Issues in Infectious Diseases, 2)

By Stefan H. E. Kaufmann , H. Hahn

Book information

Year
2002
ISBN
3805574592, 9783805574594, 9781423718291
Open Library ID
OL8938325M
Language
english
Format
PDF
Filesize
4 MB (3681315 bytes)
Edition
1
Pages
156\167
Topic
Medicine Diseases
Scanned
yes
Time added
2011-06-04 13:46:07

Description

Tuberculosis remains one of the main fatal infections in humans. With annual morbidity and mortality rates worldwide of 8 and 2 million cases respectively, the disease is far from being eradicated. In fact, the dangerous liaison between TB and HIV, and the increasing incidences of multi-drug resistant strains of Mycobacterium tuberculosis are aggravating the problem. The latest epidemiological data indicate that new drugs and a novel vaccine are urgently needed to control TB adequately. This volume summarizes the state of the art in the prevention, diagnosis and therapy of TB. In addition, the molecular biology of M. tuberculosis and the immunology of the host response are presented. Researchers are beginning to understand how the immune response controls the pathogen quite efficiently, yet fails to eradicate it completely in the 2 billion people worldwide who are infected but do not develop the disease. Finally, recent strategies towards the development of new vaccines are reviewed.

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