ENGLISH

Image Fusion in Preclinical Applications

By Claudia Kuntner-Hannes , York Haemisch

Book information

Publisher
Springer International Publishing
Year
2019
ISBN
978-3-030-02972-2, 978-3-030-02973-9
Language
english
Format
PDF
Filesize
9 MB (9600246 bytes)
Edition
1st ed.
Pages
VII, 209\212
Time added
2019-01-12 07:37:01
Medicine & Public Health; Nuclear Medicine; Medica

Description

This book provides an accessible and comprehensive overview of the state of the art in multimodal, multiparametric preclinical imaging, covering all the modalities used in preclinical research. The role of different combinations of PET, CT, MR, optical, and optoacoustic imaging methods is examined and explained for a range of applications, from research in oncology, neurology, and cardiology to drug development. Examples of animal studies are highlighted in which multimodal imaging has been pivotal in delivering otherwise unobtainable information. Hardware and software image registration methods and animal-specific factors are also discussed. The readily understandable text is enhanced by numerous informative illustrations that help the reader to appreciate the similarities to, but also the differences from, clinical applications. Image Fusion in Preclinical Applications will be of interest to all who wish to learn more about the use of multimodal/multiparametric imaging as a tool for in vivo investigations in preclinical medical and pharmaceutical research. Front Matter ....Pages i-vii High-Level Story: Data Analysis in Multimodal Preclinical Imaging—Methods and Tools (Gabriel Tobon, Jacob Hesterman, Shil Patel, Christian Lackas)....Pages 1-24 Instrumentation Challenges in (S)PE(C)T Systems (David Brasse, Frederic Boisson)....Pages 25-54 Influence of Animal Handling and Housing on Multimodality Imaging (David Stout)....Pages 55-68 Multimodal Optoacoustic Imaging (Murad Omar, Dominik Soliman, Vasilis Ntziachristos)....Pages 69-99 Small Animal Imaging in Oncology Drug Development (Joseph D. Kalen, James L. Tatum)....Pages 101-115 Investigation of Transporter-Mediated Drug-Drug Interactions Using PET/MRI (Thomas Wanek, Alexander Traxl, Claudia Kuntner-Hannes, Oliver Langer)....Pages 117-133 Multimodality Preclinical Imaging in Inflammatory Diseases (Paul D. Acton)....Pages 135-160 Preclinical Multimodality Imaging and Image Fusion in Cardiovascular Disease (James T. Thackeray)....Pages 161-181 Dual-Energy SPECT Imaging with Contrast-Enhanced CT: A Case Study (Emily B. Martin, Alan Stuckey, Stephen J. Kennel, Jonathan S. Wall)....Pages 183-196 Multimodality Imaging in Small Animal Radiotherapy (Christian Vanhove, Stefaan Vandenberghe)....Pages 197-209

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