ENGLISH

Genomic Signal Processing

By Ilya Shmulevich; Edward R. Dougherty

Book information

Publisher
Princeton University Press
Year
2007
ISBN
9781400865260, 9780691117621
LCC
QP517.C45 -- .S49 2007eb
Language
english
Format
PDF
Filesize
4 MB (4109860 bytes)
Series
Princeton Series in Applied Mathematics Ser.
Edition
1
Pages
314\314
Time added
2023-08-06 22:16:01
Cellular signal transduction. ; Genetic regulation

Description

Genomic signal processing (GSP) can be defined as the analysis, processing, and use of genomic signals to gain biological knowledge, and the translation of that knowledge into systems-based applications that can be used to diagnose and treat genetic diseases. Situated at the crossroads of engineering, biology, mathematics, statistics, and computer science, GSP requires the development of both nonlinear dynamical models that adequately represent genomic regulation, and diagnostic and therapeutic tools based on these models. This book facilitates these developments by providing rigorous mathematical definitions and propositions for the main elements of GSP and by paying attention to the validity of models relative to the data. Ilya Shmulevich and Edward Dougherty cover real-world situations and explain their mathematical modeling in relation to systems biology and systems medicine. Genomic Signal Processing makes a major contribution to computational biology, systems biology, and translational genomics by providing a self-contained explanation of the fundamental mathematical issues facing researchers in four areas: classification, clustering, network modeling, and network intervention.

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