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Advances in Immunology, Volume 133, the latest release in this long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future. Content: Series PagePage ii CopyrightPage iv ContributorsPage vii Chapter One - Macrophages and Mitochondria: A Critical Interplay Between Metabolism, Signaling, and the Functional ActivityPages 1-36J. Tur, T. Vico, J. Lloberas, A. Zorzano, A. Celada Chapter Two - Molecular Mechanisms of Somatic Hypermutation and Class Switch RecombinationPages 37-87S.P. Methot, J.M. Di Noia Chapter Three - Emerging Major Histocompatibility Complex Class I-Related Functions of NLRC5Pages 89-119S.T. Chelbi, A.T. Dang, G. Guarda Chapter Four - Nucleic Acid ImmunityPages 121-169G. Hartmann Chapter Five - About Training and Memory: NK-Cell Adaptation to Viral InfectionsPages 171-207Q. Hammer, C. Romagnani IndexPages 209-215 Contents of Recent VolumesPages 217-233
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